Evidence map›Paper›PMID 33407124›Full record

ArticleBMC immunology2021

The role of β

Tarfa Altorki, Werner Muller, Andrew Brass, Sheena Cruickshank

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Tuning immunity through tissue mechanotransduction.Nature reviews. Immunology · 2023
    Review
  6. Targeting integrin pathways: mechanisms and advances in therapy.Signal transduction and targeted therapy · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Tarfa AltorkiFaculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, A.V. Hill Building, The University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Werner MullerFaculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, A.V. Hill Building, The University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Andrew BrassFaculty of Biology, Medicine and Health, Division of Informatics, Imaging and Data Sciences, Stopford Building, The University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Sheena CruickshankFaculty of Biology, Medicine and Health, Lydia Becker Institute of Immunology and Inflammation, Manchester Academic Health Science Centre, A.V. Hill Building, The University of Manchester, Oxford Road, Manchester, M13 9PT, UK. Sheena.Cruickshank@manchester.ac.uk.
University of Manchester · GBKing Abdul Aziz University Hospital · SAManchester Academic Health Science Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDendritic cells (DCs) play a key role in shaping T cell responses. To do this, DCs must be able to migrate to the site of the infection and the lymph nodes to prime T cells and initiate the appropriate immune response. Integrins such as β

resultsIn infection, the lack of functional β

conclusionsThis data suggests that β

Indexed as

AnimalsCD18 AntigensCell MovementDendritic CellsMacrophagesMiceMice, Inbred C57BLMice, Mutant StrainsTrichuriasisTrichurisCD18 AntigensDendritic cellImmune responseInfectionMigrationβ2 integrin

Identifiers

PMID33407124
PMCPMC7789014
OpenAlexW3120587264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.