ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2021
Exogenous GLP-1 stimulates TCA cycle and suppresses gluconeogenesis and ketogenesis in late-fasted northern elephant seals pups.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Time-restricted feeding improves metabolic and endocrine profiles in mice with polycystic ovary syndrome.Frontiers in endocrinology · 2022Article
- An American Physiological Society cross-journal Call for Papers on "Inter-Organ Communication in Homeostasis and Disease".American journal of physiology. Lung cellular and molecular physiology · 2021Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
The postweaning fast of northern elephant seal pups is characterized by a lipid-dependent metabolism and associated with a decrease in plasma glucagon-like peptide-1 (GLP-1), insulin, and glucose and increased gluconeogenesis (GNG) and ketogenesis. We have also demonstrated that exogenous GLP-1 infusion increased plasma insulin despite simultaneous increases in cortisol and glucagon, which collectively present contradictory regulatory stimuli of GNG, ketogenesis, and glycolysis. To assess the effects of GLP-1 on metabolism using primary carbon metabolite profiles in late-fasted seal pups, we dose-dependently infused late-fasted seals with low (LDG; 10 pM/kg;
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