Evidence map›Paper›PMID 33406976›Full record

ReviewGut microbes

The Sporobiota of the Human Gut.

Muireann Egan, Eugene Dempsey, C Anthony Ryan, R Paul Ross, Catherine Stanton

Abstract readReview
In one paragraph

Review in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Risk analysis approaches for microbial ingredients in microbial-based cleaning products.Risk analysis : an official publication of the Society for Risk Analysis · 2025
    Article
  11. Review
  12. Article
  13. Molecular epidemiology ofMicrobial genomics · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Uncovering newMicrobiology spectrum · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muireann EganFood Biosciences Department, Teagasc Food Research Centre , Moorepark, Fermoy, Co. Cork, Ireland.
Eugene DempseyAPC Microbiome Ireland, University College Cork , Cork, Ireland.
C Anthony RyanAPC Microbiome Ireland, University College Cork , Cork, Ireland.
R Paul RossAPC Microbiome Ireland, University College Cork , Cork, Ireland.ORCID 0000-0003-4876-8839
Catherine StantonFood Biosciences Department, Teagasc Food Research Centre , Moorepark, Fermoy, Co. Cork, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gut microbiome is a diverse and complex ecosystem that plays a critical role in health and disease. The composition of the gut microbiome has been well studied across all stages of life. In recent years, studies have investigated the production of endospores by specific members of the gut microbiome. An endospore is a tough, dormant structure formed by members of the Firmicutes phylum, which allows for greater resistance to otherwise inhospitable conditions. This innate resistance has consequences for human health and disease, as well as in biotechnology. In particular, the formation of endospores is strongly linked to antibiotic resistance and the spread of antibiotic resistance genes, also known as the resistome. The term sporobiota has been used to define the spore-forming cohort of a microbial community. In this review, we present an overview of the current knowledge of the sporobiota in the human gut. We discuss the development of the sporobiota in the infant gut and the perinatal factors that may have an effect on vertical transmission from mother to infant. Finally, we examine the sporobiota of critically important food sources for the developing infant, breast milk and powdered infant formula.

Indexed as

Gastrointestinal MicrobiomeAdultDrug Resistance, BacterialEndospore-Forming BacteriaHumansInfantInfant FormulaInfectious Disease Transmission, VerticalMilk, HumanSpores, Bacterialbreast milkclostridiaearly lifeendosporesGut microbiomeinfant formulasporobiotatransmission

Identifiers

PMID33406976
PMCPMC7801112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.