Evidence map›Paper›PMID 33406919›Full record

ArticleGlobal spine journal2022

Respiratory Compromise After Anterior Cervical Spine Surgery: Incidence, Subsequent Complications, and Independent Predictors.

Venkat Boddapati, Nathan J Lee, Justin Mathew, Michael B Held, Joel R Peterson, Meghana M Vulapalli, Joseph M Lombardi, Marc D Dyrszka, Zeeshan M Sardar, Ronald A Lehman and 1 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Well-controlled asthma does not adversely affect outcomes following anterior cervical discectomy and fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Venkat BoddapatiThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0002-3333-2234
Nathan J LeeThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
Justin MathewThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0002-7699-780X
Michael B HeldThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
Joel R PetersonThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
Meghana M VulapalliThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0003-1197-0400
Joseph M LombardiThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
Marc D DyrszkaThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
Zeeshan M SardarThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
Ronald A LehmanThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
K Daniel RiewThe Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
Texas Health Dallas · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectiveRespiratory compromise (RC) is a rare but catastrophic complication of anterior cervical spine surgery (ACSS) commonly due to compressive fluid collections or generalized soft tissue swelling in the cervical spine. Established risk factors include operative duration, size of surgical exposure, myelopathy, among others. The purpose of this current study is to identify the incidence and clinical course of patients who develop RC, and identify independent predictors of RC in patients undergoing ACSS for cervical spondylosis.

methodsA large, prospectively-collected registry was used to identify patients undergoing ACSS for spondylosis. Patients with posterior cervical procedures were excluded. Baseline patient characteristics were compared using bivariate analysis, and multivariate analysis was employed to compare postoperative complications and identify independent predictors of RC.

results298 of 52,270 patients developed RC (incidence 0.57%). Patients who developed RC had high rates of 30-day mortality (11.7%) and morbidity (75.8%), with unplanned reoperation and pneumonia the most common. The most common reason for reoperations were hematoma evacuation and tracheostomy. Independent patient-specific factors predictive of RC included increasing patient age, male gender, comorbidities such as chronic cardiac and respiratory disease, preoperative myelopathy, prolonged operative duration, and 2-level ACCFs.

conclusionThis is among the largest cohorts of patients to develop RC after ACSS identified to-date and validates a range of independent predictors, many previously only described in case reports. These results are useful for taking preventive measures, identifying high risk patients for preoperative risk stratification, and for surgical co-management discussions with the anesthesiology team.

Indexed as

ACDFcervical spinecomplicationsintubationrespiratory

Identifiers

PMID33406919
PMCPMC9609542
OpenAlexW3119005172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.