Evidence map›Paper›PMID 33406897›Full record

ArticleGlobal spine journal2022

Lumbar Fusion Surgery for Patients With Back Pain and Degenerative Disc Disease: An Observational Study From the Canadian Spine Outcomes and Research Network.

Nathan Evaniew, Ganesh Swamy, W Bradley Jacobs, Jacques Bouchard, Roger Cho, Neil A Manson, Y Raja Rampersaud, Jerome Paquet, Christopher S Bailey, Michael Johnson and 4 more

Abstract read
In one paragraph

Article in Global spine journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  7. Article
  8. How Much Blood Loss Is Too Much for a 1-Level Open Lumbar Fusion?International journal of spine surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nathan EvaniewUniversity of Calgary Spine Program, University of Calgary, Alberta, Canada.ORCID 0000-0003-1974-5224
Ganesh SwamyUniversity of Calgary Spine Program, University of Calgary, Alberta, Canada.
W Bradley JacobsUniversity of Calgary Spine Program, University of Calgary, Alberta, Canada.
Jacques BouchardUniversity of Calgary Spine Program, University of Calgary, Alberta, Canada.
Roger ChoUniversity of Calgary Spine Program, University of Calgary, Alberta, Canada.
Neil A MansonCanada East Spine Centre, Saint John, New Brunswick, Canada.
Y Raja RampersaudDepartment of Surgery, University of Toronto, Ontario, Canada.
Jerome PaquetDépartement de Chirurgie, Université Laval, Quebec City, Quebec, Canada.
Christopher S BaileyDepartment of Surgery, Western University, London, Ontario, Canada.
Michael JohnsonDepartment of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.
Najmedden AttabibCanada East Spine Centre, Saint John, New Brunswick, Canada.
Charles G FisherDepartment of Orthopaedics, University of British Columbia, Vancouver, British Columbia, Canada.
Greg McIntoshCanadian Spine Outcomes and Research Network, Markdale, Ontario, Canada.ORCID 0000-0002-0268-6523
Kenneth C ThomasUniversity of Calgary Spine Program, University of Calgary, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designUncontrolled retrospective observational study.

objectivesSurgery for patients with back pain and degenerative disc disease is controversial, and studies to date have yielded conflicting results. We evaluated the effects of lumbar fusion surgery for patients with this indication in the Canadian Spine Outcomes and Research Network (CSORN).

methodsWe analyzed data that were prospectively collected from consecutive patients at 11 centers between 2015 and 2019. Our primary outcome was change in patient-reported back pain at 12 months of follow-up, and our secondary outcomes were satisfaction, disability, health-related quality of life, and rates of adverse events.

resultsAmong 84 patients, we observed a statistically significant improvement of back pain at 12 months that exceeded the threshold of Minimum Clinically Important Difference (MCID) (mean change -3.7 points, SD 2.6, p < 0.001, MCID = 1.2; 77% achieved MCID), and 81% reported being "somewhat" or "extremely" satisfied. We also observed improvements of Oswestry Disability Index (-17.3, SD 16.6), Short Form-12 Physical Component Summary (10.3, SD 9.6) and Short Form-12 Mental Component Summary (3.1, SD 8.3); all p < 0.001). The overall rate of adverse events was 19%.

conclusionsAmong a highly selective group of patients undergoing lumbar fusion surgery for degenerative disc disease, most experienced a clinically significant improvement of back pain as well as significant improvements of disability and health-related quality of life, with high satisfaction at 1 year of follow-up. These findings suggest that surgery for this indication may provide some benefit, and that further research is warranted.

Indexed as

back paindegenerative disc diseasefusionlumbaroperationspine surgery

Identifiers

PMID33406897
PMCPMC9609527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.