Evidence map›Paper›PMID 33406796›Full record

ArticleAnimals : an open access journal from MDPI2021

Urinary Excretion of Iohexol as a Permeability Marker in a Mouse Model of Intestinal Inflammation: Time Course, Performance and Welfare Considerations.

Victoria Ortín-Piqueras, Tobias L Freitag, Leif C Andersson, Sanna H Lehtonen, Seppo K Meri, Thomas Spillmann, Rafael Frias

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Victoria Ortín-PiquerasDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, FIN-00014 Helsinki, Finland.ORCID 0000-0001-6969-4993
Tobias L FreitagTranslational Immunology Research Program, University of Helsinki, FIN-00014 Helsinki, Finland.
Leif C AnderssonDepartment of Pathology, University of Helsinki, FIN-00014 Helsinki, Finland.
Sanna H LehtonenDepartment of Pathology, University of Helsinki, FIN-00014 Helsinki, Finland.ORCID 0000-0003-4189-2415
Seppo K MeriTranslational Immunology Research Program, University of Helsinki, FIN-00014 Helsinki, Finland.ORCID 0000-0001-9142-501X
Thomas SpillmannDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, FIN-00014 Helsinki, Finland.ORCID 0000-0002-0176-7428
Rafael FriasComparative Medicine, Karolinska Institute, SE-171 77 Stockholm, Sweden.
University of Helsinki · FIKarolinska Institutet · SE

Funding

Academy of Finland grant 292393
6 · The paper itself

Abstract

Intestinal permeability (IP) tests are used to assess intestinal damage in patients and research models. The probe iohexol has shown advantages compared to

Indexed as

duodenitisinflammationintestinal permeabilityiohexolmetabolic cagemousepermeability testingsmall intestine

Identifiers

PMID33406796
PMCPMC7824797
OpenAlexW3120862745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.