Evidence map›Paper›PMID 33406681›Full record

ArticleInternational journal of molecular sciences2021

Intracellular and Extracellular Markers of Lethality in Osteogenesis Imperfecta: A Quantitative Proteomic Approach.

Luca Bini, Domitille Schvartz, Chiara Carnemolla, Roberta Besio, Nadia Garibaldi, Jean-Charles Sanchez, Antonella Forlino, Laura Bianchi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  11. The extracellular matrix glycoprotein fibrillin-1 in health and disease.Frontiers in cell and developmental biology · 2023
    Review
  12. Article
  13. Neurodegenerative Disorder Risk in Krabbe Disease Carriers.International journal of molecular sciences · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Luca BiniFunctional Proteomics Laboratory, Department of Life Sciences, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-8951-2106
Domitille SchvartzDivision of Laboratory Medicine, Department of Medicine, University Medical Center, 1206 Geneva, Switzerland.ORCID 0000-0003-1133-0462
Chiara CarnemollaFunctional Proteomics Laboratory, Department of Life Sciences, University of Siena, 53100 Siena, Italy.
Roberta BesioBiochemistry Unit, Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-1430-2934
Nadia GaribaldiBiochemistry Unit, Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-0353-537X
Jean-Charles SanchezDivision of Laboratory Medicine, Department of Medicine, University Medical Center, 1206 Geneva, Switzerland.
Antonella ForlinoBiochemistry Unit, Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.
Laura BianchiFunctional Proteomics Laboratory, Department of Life Sciences, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-9219-1227
University of Pavia · ITUniversity of Siena · IT

Funding

Fondazione Cariplo grant n. 2013-0612Fondazione Telethon GGP13098
6 · The paper itself

Abstract

Osteogenesis imperfecta (OI) is a heritable disorder that mainly affects the skeleton. The inheritance is mostly autosomal dominant and associated to mutations in one of the two genes,

Indexed as

BiomarkersChild, PreschoolChromatography, LiquidCollagen Type ICollagen Type I, alpha 1 ChainFemaleHumansInfantInfant, NewbornMaleMutationOsteogenesis ImperfectaProteomeTandem Mass SpectrometryBiomarkersCOL1A2 protein, humanCollagen Type ICollagen Type I, alpha 1 ChainProteomebioinformaticscell signalingcytoskeletonextracellular matrixosteogenesis imperfectapathway analysisREVIGO

Identifiers

PMID33406681
PMCPMC7795927
OpenAlexW3118818552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.