Evidence map›Paper›PMID 33406665›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Multimodal MRI Assessment of Thalamic Structural Changes in Earthquake Survivors.

Federico Bruno, Alessandra Splendiani, Emanuele Tommasino, Massimiliano Conson, Mario Quarantelli, Gennaro Saporito, Antonio Carolei, Simona Sacco, Ernesto Di Cesare, Antonio Barile and 2 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Structural brain correlates of childhood trauma with replication across two large, independent community-based samples.European psychiatry : the journal of the Association of European Psychiatrists · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Federico BrunoDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0002-1444-2585
Alessandra SplendianiDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0002-2188-3506
Emanuele TommasinoDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0003-1523-8081
Massimiliano ConsonLaboratory of Developmental Neuropsychology, Department of Psychology, University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.ORCID 0000-0002-4776-306X
Mario QuarantelliInstitute of Biostructure and Bioimaging, National Research Council, 80100 Naples, Italy.ORCID 0000-0001-7836-454X
Gennaro SaporitoDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Antonio CaroleiDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Simona SaccoDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Ernesto Di CesareDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Antonio BarileDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Carlo MasciocchiDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Francesca PistoiaDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0003-0790-4240
University of L'Aquila · ITInstitute of Biostructure and Bioimaging · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moving from the central role of the thalamus in the integration of inner and external stimuli and in the implementation of a stress-related response, the objective of the present study was to investigate the presence of any MRI structural and volumetric changes of the thalamic structures in earthquake witnesses. Forty-one subjects were included, namely 18 university students belonging to the experimental earthquake-exposed group (8 males and 10 females, mean age 24.5 ± 1.8 years) and a control group of 23 students not living in any earthquake-affected areas at the time of the earthquake (14 males and 9 females, mean age 23.7 ± 2.0 years). Instrumental MRI evaluation was performed using a 3-Tesla scanner, by acquiring a three-dimensional fast spoiled gradient-echo (FSPGR) sequence for volumetric analysis and an EPI (echoplanar imaging) sequence to extract fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values. As compared to the control one, the experimental group showed significantly lower gray matter volume in the mediodorsal nucleus of the left thalamus (

Indexed as

brain volumesDTIDWIearthquakeMRIstressthalamustrauma

Identifiers

PMID33406665
PMCPMC7824088
OpenAlexW3118700734

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.