Evidence map›Paper›PMID 33406591›Full record

ArticleFoods (Basel, Switzerland)2021

Investigation of the Distribution and Content of Acetylcholine, a Novel Functional Compound in Eggplant.

Wenhao Wang, Shohei Yamaguchi, Ayako Suzuki, Naomi Wagu, Masahiro Koyama, Akihiko Takahashi, Risa Takada, Koji Miyatake, Kozo Nakamura

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Wenhao WangDepartment of Science and Technology, Graduate School of Medicine, Science and Technology, Shinshu University, 8304, Minamiminowa, Nagano 399-4598, Japan.
Shohei YamaguchiDepartment of Science and Technology, Graduate School of Medicine, Science and Technology, Shinshu University, 8304, Minamiminowa, Nagano 399-4598, Japan.
Ayako SuzukiMidorigaoka Junior High School, 426, Kega, Iida, Nagano 395-0813, Japan.
Naomi WaguDepartment of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, 8304, Minamiminowa, Nagano 399-4598, Japan.
Masahiro KoyamaWellnas Co., Ltd., Toranomon Masters Building 6F, 1-12-14, Toranomon, Minato-ku, Tokyo 105-0001, Japan.
Akihiko TakahashiKochi Agricultural Research Center, 1100 Hataeda, Nankoku, Kochi 783-0023, Japan.
Risa TakadaSaladcosmo. Co., Ltd., 1-15, Sendambayashi, Nakatsugawa, Gifu 509-9131, Japan.
Koji MiyatakeInstitute of Vegetable and Floriculture Science, NARO, 360 Kusawa, Ano-cho, Tsu, Mie 514-2392, Japan.
Kozo NakamuraDepartment of Science and Technology, Graduate School of Medicine, Science and Technology, Shinshu University, 8304, Minamiminowa, Nagano 399-4598, Japan.
Shinshu University · JPInstitute of Vegetable and Floriculture Science · JPKochi Agricultural Technology Center · JPNiigata Prefectural Niigata MidoriKo High School · JPToranomon Hospital · JP

Funding

Kozo Nakamura 16932813
6 · The paper itself

Abstract

Eggplants are rich in acetylcholine (ACh), which can improve high blood pressure and negative psychological states. However, information on ACh content in individual parts of eggplant and the changes in ACh content during eggplant development is limited. Therefore, we investigated the ACh content in various parts of eggplant, namely, the leaf, root, bud, calyx, ovary, fruit, exocarp, mesocarp, partition, placenta, core, fruit base, fruit center, and fruit top in 26 eggplant varieties. Furthermore, the effect of heat treatment on ACh content was investigated. The ACh content significantly differed among the eggplant varieties. The difference between the varieties with the highest and lowest ACh content was 100-fold (Tosataka: 11 ± 0.61 mg/100 g fresh weight (FW) and Ryoma: 0.11 ± 0.046 mg/100 g FW, respectively). Eggplant fruit presented the highest ACh content (4.8 mg/100 g FW); it was three times higher than that in other parts combined (1.6 mg/100 g FW). The root contained the lowest ACh content among all parts. The ACh content increased with growth after flowering. The ACh content in the fruit 1.5 months after flowering was 400 times that in the ovary. ACh was uniformly distributed in eggplant flesh. Heat treatment did not cause ACh loss in eggplant. Thus, eggplant is an excellent raw material for functional foods.

Indexed as

acetylcholinecholinecholine estercookingeggplanteggplant partfunctional foodLC–MS/MS

Identifiers

PMID33406591
PMCPMC7823263
OpenAlexW3119965888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.