Evidence map›Paper›PMID 33405360›Full record

ArticleChembiochem : a European journal of chemical biology2020

The Impact of Halogenated Phenylalanine Derivatives on NFGAIL Amyloid Formation.

Suvrat Chowdhary, Johann Moschner, Dorian J Mikolajczak, Maximilian Becker, Andreas F Thünemann, Claudia Kästner, Damian Klemczak, Anne-Katrin Stegemann, Christoph Böttcher, Pierangelo Metrangolo and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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  9. The Impact of Halogenated Phenylalanine Derivatives on NFGAIL Amyloid Formation.Chembiochem : a European journal of chemical biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Suvrat ChowdharyInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.ORCID 0000-0001-8669-4362
Johann MoschnerInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
Dorian J MikolajczakInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
Maximilian BeckerDepartment of Physics, Freie Universität Berlin, Arnimallee 14, 14195, Berlin, Germany.
Andreas F ThünemannFederal Institute for Materials Research and Testing (BAM), Unter den Eichen 87, 12205, Berlin, Germany.
Claudia KästnerFederal Institute for Materials Research and Testing (BAM), Unter den Eichen 87, 12205, Berlin, Germany.
Damian KlemczakInstitute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2-4, 14195, Berlin, Germany.
Anne-Katrin StegemannInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
Christoph BöttcherInstitute of Chemistry and Biochemistry and Core Facility BioSupraMol, Freie Universität Berlin, Fabeckstraße 36a, 14195, Berlin, Germany.
Pierangelo MetrangoloDepartment of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Via L. Mancinelli 7, 20131, Milan, Italy.
Roland R NetzDepartment of Physics, Freie Universität Berlin, Arnimallee 14, 14195, Berlin, Germany.
Beate KokschInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
Freie Universität Berlin · DEFederal Institute For Materials Research and Testing · DEPolitecnico di Milano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hexapeptide hIAPP

Indexed as

Density Functional TheoryHalogenationHumansHydrocarbons, HalogenatedHydrophobic and Hydrophilic InteractionsIslet Amyloid PolypeptideKineticsMolecular StructureParticle SizePhenylalanineProtein AggregatesHydrocarbons, HalogenatedIslet Amyloid PolypeptidePhenylalanineProtein Aggregatesbeta-amyloid fibrilsfluorescencefluorinated phenylalaninefluorineNFGAIL

Identifiers

PMID33405360
PMCPMC7756607
OpenAlexW3046371157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.