Evidence map›Paper›PMID 33405196›Full record

ArticleJournal of molecular neuroscience : MN2021

Chronic Neuroinflammation Induced by Lipopolysaccharide Injection into the Third Ventricle Induces Behavioral Changes.

Shufang Na, Xuejiao Duan, Rongyan Wang, Yanjie Fan, Ke Xue, Shuwei Tian, Zheqiong Yang, Ke Li, Jiang Yue

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shufang Na *Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Xuejiao Duan *Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Rongyan WangDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Yanjie FanDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Ke XueDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Shuwei TianDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Zheqiong YangDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China.
Ke LiDemonstration Center for Experimental Basic Medicine Education, Wuhan University, Wuhan, 430071, China.
Jiang YueDepartment of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, China. yuejiang@whu.edu.cn.ORCID http://orcid.org/0000-0001-8906-1253
Wuhan University · CN

Funding

National Natural Science Foundation of China 81173122National Natural Science Foundation of China 81673503
6 · The paper itself

Abstract

The existence of Gram-negative bacteria in the brain, regardless of underlying immune status has been demonstrated by recent studies. The colocalization of lipopolysaccharide (LPS) with Aβ

Indexed as

Maze LearningAnimalsCell Line, TumorCholesterolCholesterol 24-HydroxylaseEncephalitisHippocampusHumansHydroxymethylglutaryl CoA ReductasesInjections, IntraventricularInterleukin-1betaLipopolysaccharidesMaleRatsRats, Wistartau ProteinsCholesterolCholesterol 24-HydroxylaseHydroxymethylglutaryl CoA ReductasesInterleukin-1betaLipopolysaccharidestau ProteinsTlr4 protein, ratToll-Like Receptor 4Tumor Necrosis Factor-alphaAlzheimer’s diseaseCholesterolDepressionNeuroinflammationTau

Identifiers

PMID33405196
OpenAlexW3119573868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.