Evidence map›Paper›PMID 33404964›Full record

ArticleSleep & breathing = Schlaf & Atmung2021

Differential relationship of two measures of sleepiness with the drives for sleep and wake.

Vladimir B Dorokhov, Dmitry S Sveshnikov, Alexandra N Puchkova, Anton I Taranov, Dmitry S Sakharov, Svetlana S Gruzdeva, Olga N Tkachenko, Gleb N Arsen'ev, Natalya V Ligun, Valeriy V Dementienko and 6 more

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Vladimir B DorokhovLaboratory of Sleep/Wake Neurobiology, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia.
Dmitry S SveshnikovDepartment of Normal Physiology, Medical Institute of the Peoples' Friendship University of Russia, Moscow, Russia.
Alexandra N PuchkovaLaboratory of Sleep/Wake Neurobiology, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia.
Anton I TaranovLaboratory of Sleep/Wake Neurobiology, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia.
Dmitry S SakharovLaboratory of Sleep/Wake Neurobiology, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia.
Svetlana S GruzdevaLaboratory of Sleep/Wake Neurobiology, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia.
Olga N TkachenkoLaboratory of Sleep/Wake Neurobiology, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia.
Gleb N Arsen'evLaboratory of Sleep/Wake Neurobiology, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia.
Natalya V LigunLaboratory of Sleep/Wake Neurobiology, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia.
Valeriy V DementienkoLaboratory of Medical Electronics, Kotelnikov Institute of Radio Engineering and Electronics, Russian Academy of Science, Moscow, Russia.
Zarina B BakaevaDepartment of Normal Physiology, Medical Institute of the Peoples' Friendship University of Russia, Moscow, Russia.
Elena B YakuninaDepartment of Normal Physiology, Medical Institute of the Peoples' Friendship University of Russia, Moscow, Russia.
Yuri P StarshinovDepartment of Normal Physiology, Medical Institute of the Peoples' Friendship University of Russia, Moscow, Russia.
Vladimir I TorshinDepartment of Normal Physiology, Medical Institute of the Peoples' Friendship University of Russia, Moscow, Russia.
Olga G DonskayaResearch Group for Math-Modeling of Biomedical Systems, Research Institute for Molecular Biology and Biophysics of the Federal Research Centre for Fundamental and Translational Medicine, Novosibirsk, Russia.
Arcady A PutilovLaboratory of Sleep/Wake Neurobiology, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia. putilov@ngs.ru.ORCID 0000-0003-2779-9046

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSince disagreement has been found between an objective sleep propensity measured by sleep onset latency (SOL) and subjective sleepiness assessment measured by the Epworth sleepiness scale (ESS) score, distinct underlying causes and consequences were suggested for these two sleepiness measures. We addressed the issue of validation of the ESS against objective sleepiness and sleep indexes by examining the hypothesis that these two sleepiness measures are disconnected due to their differential relationship with the antagonistic drives for sleep and wake.

methodsThe polysomnographic records of 50-min napping attempts were collected from 27 university students on three occasions. Scores on the first and second principal components of the electroencephalographic (EEG) spectrum were calculated to measure the sleep and wake drives, respectively. Self-assessments of subjective sleepiness and sleep were additionally collected in online survey of 633 students at the same university.

resultsAn ESS score was disconnected with the polysomnographic and self-assessed SOL in the nap study and online survey, respectively. An ESS score but not SOL was significantly linked to the spectral EEG measure of the sleep drive, while SOL but not ESS showed a significant association with the spectral EEG measure of the opposing wake drive.

conclusionsEach of two sleepiness measures was validated against objective indicators of the opposing sleep-wake regulating processes, but different underlying causes were identified for two distinct aspects of sleepiness. A stronger sleep drive and a weaker opposing drive for wake seem to contribute to a higher ESS score and to a shorter SOL, respectively.

Indexed as

AdultCerebral CortexElectroencephalographyFemaleHumansMalePolysomnographySleepinessWakefulnessYoung AdultAlertness;Drowsiness;ESS;Principal component analysisSpectral EEG;

Identifiers

PMID33404964

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.