Evidence map›Paper›PMID 33404807›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Assessing the financial toxicity in Tunisian cancer patients using the Comprehensive Score for Financial Toxicity (COST).

Nesrine Mejri, Yosra Berrazega, Ryma Boujnah, Haifa Rachdi, Houda El Benna, Soumaya Labidi, Hamouda Boussen

Abstract read
PubMed Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Evaluation of financial toxicity and associated factors in female patients with breast cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Financial toxicity and associated factors among cancer patients attending public hospitals in Ethiopia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  9. Exploring financial toxicity and its impact on health-related quality of life of cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Financial toxicity assessment and associated factors analysis of patients with cancer in China.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  14. Observational
  15. Article
  16. Patient-reported benefit from proposed interventions to reduce financial toxicity during cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  17. Article
  18. Correlates of financial toxicity in adult cancer patients and their informal caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nesrine MejriMedical Oncology Department, Abderrahmen Mami Hospital, University of Medicine, University Tunis El Manar, Tunis, Tunisia. nesrinemejriturki2@gmail.com.ORCID http://orcid.org/0000-0001-7647-5027
Yosra BerrazegaMedical Oncology Department, Abderrahmen Mami Hospital, University of Medicine, University Tunis El Manar, Tunis, Tunisia.
Ryma BoujnahMedical Oncology Department, Abderrahmen Mami Hospital, University of Medicine, University Tunis El Manar, Tunis, Tunisia.
Haifa RachdiMedical Oncology Department, Abderrahmen Mami Hospital, University of Medicine, University Tunis El Manar, Tunis, Tunisia.
Houda El BennaMedical Oncology Department, Abderrahmen Mami Hospital, University of Medicine, University Tunis El Manar, Tunis, Tunisia.
Soumaya LabidiMedical Oncology Department, Abderrahmen Mami Hospital, University of Medicine, University Tunis El Manar, Tunis, Tunisia.
Hamouda BoussenMedical Oncology Department, Abderrahmen Mami Hospital, University of Medicine, University Tunis El Manar, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer care-related out-of-pocket expenses and financial toxicity (FT) are a rising burden for patients. We aimed to evaluate patient-reported FT and to identify relevant correlates within a Tunisian population.

methodsWe conducted a survey using the 11-item Comprehensive Score for Financial Toxicity (COST) that could range from 0 = high to 44 = low. FT was grade 0 if ≥ 26, grade 1 = (14-25), grade 2 = (1-13), and grade 3 = 0. Scores were collected along with data regarding patient medical/social features and out-of-pocket expenses. Univariate and multivariate analyses were performed to identify factors associated with higher financial burden.

resultsAmong the 179 participants, median COST score was 20.8 (Q1 17-Q3 24), with 80.4% of patients experiencing financial toxicity: grade 0 = 20%, grade 1 = 68.4%, grade 2 = 11.7%, grade 3 = 0%. Most patients (66.5%) used to work before cancer and 44.7% reported ceasing work because of cancer. The time to go to the hospital was > 30 min in 66.5% of cases. Unemployment, time to hospital > 30 min, ceasing work because of cancer, and expenses on non-chemotherapy drugs exceeding 70 dinars (25 US dollars) were mostly associated with higher FT on univariate analysis. Distance to hospital and ceasing work because of cancer were the single most significant factors in multivariate analysis.

conclusionsLosing work due to cancer and unequal distribution of health care particularly in cities with long travel times to the nearest hospital are the main sources of financial distress.

Indexed as

Cost of IllnessAdultAgedAged, 80 and overFemaleFinancial StressHealth ExpendituresHumansMaleMiddle AgedNeoplasmsPatientsSurveys and QuestionnairesTunisiaUnemploymentYoung AdultCancerChemotherapyCohort studyFinancial toxicityPatient-reported outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.