ArticleInternational archives of occupational and environmental health2021
Longitudinal predictors of bronchial hyperresponsiveness and FEV
Article in International archives of occupational and environmental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors at 2 institutions in 1 country.
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Abstract
objectiveTo determine long-term predictors of bronchial hyperresponsiveness (BHR) and forced expiratory volume in one second (FEV
methodsA longitudinal study in 110 bakers in 4 industrial bakeries and 38 non-exposed workers was conducted at the workplace with a mean of 3.3 visits per subject over a period of 13 years and a mean duration of follow-up of 6 years in bakers and 8 years in non-exposed subjects. A respiratory health questionnaire was administered; occupational allergen skin prick tests, spirometry and a methacholine bronchial challenge test were performed at each visit. In each bakery, full-shift dust samples of the inhalable fraction were obtained in order to assess the exposure of each job assignment. The repeated measurements of BHR and FEV
resultsBHR, respiratory symptoms and their simultaneous occurrence depended on the duration of exposure. FEV
conclusionIn flour-exposed industrial bakers, length of exposure and smoking are long-term determinants of BHR and of the decrease in FEV
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