ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021
Arteriovenous malformation surgery in children: the Rady Children's Hospital experience (2002-2019).
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Treatment outcomes of Spetzler-Ponce grade A brain AVMs in a low-volume center: a systematic review and single institution experience.Neurosurgical review · 2025Pooled it
- Recurrence of Angiographically Cured AVMs: Influence of Age, Angioarchitecture, and Hemorrhagic Presentation and Implications for Follow-Up.Stroke (Hoboken, N.J.) · 2026Article
- Young stroke: An update on epidemiology, emerging risk factors, and future research directions.International journal of stroke : official journal of the International Stroke Society · 2026Review
- Pediatric Brain AVM: The Role of DSA During Surgery in Hybrid Operating Room.Advances and technical standards in neurosurgery · 2026Article
- Natural History and Predictors for Hemorrhage in Supratentorial Brain Arteriovenous Malformations.Journal of clinical medicine · 2024Article
- Multi-modality treatment approach for paediatric AVMs with quality-of-life outcome measures.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
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Authors and funding
9 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeCompared to adult AVMs, there is a paucity of data on the microsurgical treatment of pediatric AVMs. We report our institutional experience with pediatric AVMs treated by microsurgical resection with or without endovascular embolization and radiation therapy.
methodsWe retrospectively reviewed all patients ≤ 18 years of age with cerebral AVMs that underwent microsurgical resection at Rady Children's Hospital 2002-2019.
resultsEighty-nine patients met inclusion criteria. The mean age was 10.3 ± 5.0 years, and 56% of patients were male. In total, 72 (81%) patients presented with rupture. Patients with unruptured AVMs presented with headache (n = 5, 29.4%), seizure (n = 9, 52.9%), or incidental finding (n = 3, 17.7%). The mean presenting mRS was 2.8 ± 1.8. AVM location was lobar in 78%, cerebellar/brainstem in 15%, and deep supratentorial in 8%. Spetzler-Martin grade was I in 28%, II in 45%, III in 20%, IV in 6%, and V in 1%. Preoperative embolization was utilized in 38% of patients and more frequently in unruptured than ruptured AVMs (62% vs. 32%, p = 0.022). Radiographic obliteration was achieved in 76/89 (85.4%) patients. Complications occurred in 7 (8%) patients. Annualized rates of delayed rebleeding and recurrence were 1.2% and 0.9%, respectively. The mean follow-up was 2.8 ± 3.1 years. A good neurological outcome (mRS score ≤ 2) was obtained in 80.9% of patients at last follow-up and was improved relative to presentation for 75% of patients.
conclusionsOur case series demonstrates high rates of radiographic obliteration and relatively low incidence of neurologic complications of treatment or AVM recurrence.
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