Evidence map›Paper›PMID 33404694›Full record

SynthesisAnnals of hematology2021

Comparison of the efficiency, safety, and survival outcomes in two stem cell mobilization regimens with cyclophosphamide plus G-CSF or G-CSF alone in multiple myeloma: a meta-analysis.

Liwen Wang, Hongxian Xiang, Yuhan Yan, Zuqun Deng, Hui Li, Xin Li, Jing Liu

Erratum issuedOpen access · hybridAbstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Annals of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Low Dose Cyclophospahamide is a Feasable Mobilization Regimen in the Covid-19 Era: A Single Center Study from Türkiye.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Automated chemotherapy compounding: Process optimization for the preparation of admixture containing high-dose of cyclophosphamide.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2023
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Liwen WangDepartment of Hematology, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan Province, China.
Hongxian XiangDepartment of Hematology, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan Province, China.
Yuhan YanDepartment of Hematology, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan Province, China.
Zuqun DengDepartment of Hematology, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan Province, China.
Hui LiAssisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, Zhejiang Province, China.
Xin LiDepartment of Hematology, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan Province, China.
Jing LiuDepartment of Hematology, Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan Province, China. lj0jingliu@163.com.ORCID http://orcid.org/0000-0002-7366-5287
Central South University · CNSir Run Run Shaw Hospital · CN

Funding

National Natural Science Foundation of China 81870166
6 · The paper itself

Abstract

Autologous stem cell transplantation as a frontline treatment for patients with multiple myeloma (MM) requires an adequate peripheral blood stem cell (PBSC) collection before processing. Granulocyte-colony stimulating factor (G-CSF) with or without cyclophosphamide (CTX) is a common regimen for PBSC mobilization; their benefits and risks are controversial. To compare the efficiency, safety, and survival outcomes between the two regimens, we conducted a meta-analysis including 18 studies with 4 prospective and 14 retrospective studies; a total of 2770 patients with MM were analyzed. The CTX plus G-CSF regimen had higher yields of total CD34

Indexed as

Hematopoietic Stem Cell MobilizationHematopoietic Stem Cell TransplantationMultiple MyelomaSafetyAutograftsCyclophosphamideDisease-Free SurvivalGranulocyte Colony-Stimulating FactorHumansSurvival RateCyclophosphamideGranulocyte Colony-Stimulating FactorCyclophosphamideEvent-free survivalGranulocyte-colony stimulating factorMultiple myelomaStem cell mobilization

Identifiers

PMID33404694
PMCPMC7817584
OpenAlexW3119673538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.