Evidence map›Paper›PMID 33404670›Full record

ArticleSkeletal radiology2021

Impact of different physical activity types on knee joint structural degeneration assessed with 3-T MRI in overweight and obese subjects: data from the osteoarthritis initiative.

S Schirò, S C Foreman, G B Joseph, R B Souza, C E McCulloch, M C Nevitt, T M Link

Open access · greenAbstract read
In one paragraph

Article in Skeletal radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Exercise approaches in obese individuals with physical limitations.Turkish journal of physical medicine and rehabilitation · 2026
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

S SchiròDepartment of Radiology and Biomedical Imaging, University of California San Francisco, 185 Berry St, San Francisco, CA, 94107, USA. silvischiro@gmail.com.ORCID http://orcid.org/0000-0001-9608-1308
S C ForemanDepartment of Radiology and Biomedical Imaging, University of California San Francisco, 185 Berry St, San Francisco, CA, 94107, USA.
G B JosephDepartment of Radiology and Biomedical Imaging, University of California San Francisco, 185 Berry St, San Francisco, CA, 94107, USA.
R B SouzaDepartment of Radiology and Biomedical Imaging, Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, CA, USA.
C E McCullochDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
M C NevittDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
T M LinkDepartment of Radiology and Biomedical Imaging, University of California San Francisco, 185 Berry St, San Francisco, CA, 94107, USA.
University of California, San Francisco · USUniversity of Parma · IT

Funding

ZIDOVUDINE &LAMIVUDINE &NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFM01RR001271 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KESSLER, DAVID A · 1985 to 2006
$22.7M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
Skeletal Biology and Biomechanics (SBB) CoreP30AR075055 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EDWARD C HSIAO · 2019 to 2026
$7.1M
Impact of Weight loss on Knee Joint Biochemical and Structural DegenerationR01AR064771 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LINK, THOMAS M · 2014 to 2019
$1.6M
Mentoring Biomechanics Research in OsteoarthritisK24AR072133 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Richard Brian Souza · 2018 to 2026
$1.5M
NCRR NIH HHS M01 RR001271NIAMS NIH HHS K24 AR072133NIAMS NIH HHS P30 AR075055NIAMS NIH HHS R01 AR064771NIDDK NIH HHS P30 DK098722NIH HHS NIH/NIAMS R01-AR064771
6 · The paper itself

Abstract

objectiveTo assess the impact of different types of physical activity types on longitudinal knee joint structural changes over 48 months in overweight and obese subjects. MATERIALS AND

methodsWe included 415 subjects with a BMI ≥ 25 kg/m

resultsNo significant differences in epidemiological data were found between the groups except for gender composition, and there were no significant differences in baseline WORMS. In the cohort as a whole and most exercise groups overall WORMS significantly increased during the observational period. Highest increases compared to the remainder of the group were found in the high impact group (increase in WORMS 4.65; [95% CI] [3.94,5.35]; p = 0.040) and the racquet sports group (6.39; [95% CI] [5.13,7.60]; p ≤ 0.001). Subjects using an elliptical-trainer showed the lowest increase in WORMS (- 1.50 [- 0.21, 3.22]; p = 0.002).

conclusionProgression of knee joint degeneration was consistently higher in subjects engaging in high-impact and racquet sports while subjects using an elliptical-trainer showed the smallest changes in structural degeneration. This work was presented during the 2020 Radiological Society of North America Annual meeting.

Indexed as

Cartilage, ArticularOsteoarthritis, KneeExerciseHumansKnee JointMagnetic Resonance ImagingNorth AmericaObesityOverweightKnee articular cartilageKnee osteoarthritisMRIObesityPhysical activity

Identifiers

PMID33404670
PMCPMC8122031
OpenAlexW3119102350

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.