Evidence map›Paper›PMID 33404377›Full record

ArticleEating disorders

Genetic and environmental influences on posttraumatic stress disorder symptoms and disinhibited eating behaviors.

Niloofar Afari, Marianna Gasperi, Cara Dochat, Jennalee S Wooldridge, Matthew S Herbert, Ellen A Schur, Dedra S Buchwald

Open access · greenAbstract read
In one paragraph

Article in Eating disorders. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Niloofar AfariVA Center of Excellence for Stress and Mental Health, San Diego, California, USA.ORCID https://orcid.org/0000-0002-6489-378X
Marianna GasperiVA Center of Excellence for Stress and Mental Health, San Diego, California, USA.ORCID https://orcid.org/0000-0003-4112-5232
Cara DochatDepartment of Mental Health, Department of Research, VA San Diego Healthcare System, San Diego, California, USA.
Jennalee S WooldridgeVA Center of Excellence for Stress and Mental Health, San Diego, California, USA.ORCID https://orcid.org/0000-0002-2815-5974
Matthew S HerbertVA Center of Excellence for Stress and Mental Health, San Diego, California, USA.ORCID https://orcid.org/0000-0001-7395-6271
Ellen A SchurDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Dedra S BuchwaldElson S Floyd College of Medicine, Washington State University, Spokane, Washington, USA.
University of California San Diego · USSan Diego State University · USUniversity of Washington · USWashington State University Spokane · US

Funding

Building a Unique National Community Based Twin RepositoryRC2HL103416 · NHLBI · UNIVERSITY OF WASHINGTON · PI BUCHWALD, DEDRA S · 2009 to 2010
$7.7M
An ACT-enhanced Weight Management and Fitness Program for Navy PersonnelR01DK106415 · NIDDK · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI AFARI, NILOOFAR · 2016 to 2020
$2.5M
Chronic pain conditions and internalizing psychopathology, a genetic epidemiology investigation.IK2CX002107 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Marianna Gasperi · 2021 to 2026
–
Mindful Action for Pain: An Integrated Approach to Improve Chronic Pain FunctionIK2RX002807 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI HERBERT, MATTHEW · 2019 to 2023
–
CSRD VA IK2 CX002107NHLBI NIH HHS RC2 HL103416NIDDK NIH HHS R01 DK106415RRD VA IK2 RX002807
6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) and eating disorders (ED) frequently co-occur, but the mechanisms underlying this association remain unclear. EDs are characterized by features of maladaptive eating behaviors including disinhibited eating and cognitive dietary restraint. Identifying the genetic overlap between PTSD symptoms and maladaptive eating behaviors may elucidate biological mechanisms and potential treatment targets. A community sample of 400 same-sex twins (102 monozygotic and 98 dizygotic pairs) completed the PTSD Checklist-Civilian (PCL-C) for PTSD symptoms and the Three-Factor Eating Questionnaire-Reduced (TFEQ-R18) for eating behaviors (uncontrolled eating, emotional eating, and cognitive dietary restraint). We used biometric modeling to examine the genetic and environmental relationships between PCL-C and TFEQ-R18 total and subscales scores. Heritability was estimated at 48% for PTSD symptoms and 45% for eating behavior overall. Bivariate models revealed a significant genetic correlation between PTSD symptoms and eating behavior overall (

Indexed as

Feeding and Eating DisordersStress Disorders, Post-TraumaticEmotionsFeeding BehaviorHumansSurveys and Questionnaires

Identifiers

PMID33404377
PMCPMC8257777
OpenAlexW3120024749

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.