Evidence map›Paper›PMID 33404362›Full record

ArticleRadiology2021

Early-Stage Alzheimer Disease Image-guided Therapy Clinical Trial Serendipity: Glymphatic Efflux and Prolonged Meningeal Venous Permeability Enhancement.

Alexander L Klibanov

Abstract readEditorialComment
In one paragraph

Article in Radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Alexander L KlibanovFrom the Cardiovascular Division and Robert M. Berne Cardiovascular Research Center, University of Virginia, 409 Lane Rd, Charlottesville VA 22908.ORCID 0000-0001-9061-9971

Funding

Ultrasound-triggered red blood cell drug delivery with photoacoustic trackingR01EB023055 · NIBIB · UNIVERSITY OF VIRGINIA · PI KLIBANOV, ALEXANDER L · 2017 to 2020
$2.3M
Ultrasound Enhanced Low Dose Drug Delivery: Quantifying Uptake, Retention and BiodistributionR44HL139241 · NHLBI · SOUNDPIPE, LLC · PI KILROY, JOSEPH P. · 2017 to 2018
$2.0M
Macrophages as modulators of repair after neonatal strokeR01NS076726 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VEXLER, ZINAIDA S · 2012 to 2016
$1.8M
NHLBI NIH HHS R44 HL139241NIBIB NIH HHS R01 EB023055NINDS NIH HHS R01 NS076726
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseLymphatic VesselsBrainHumansPermeability

Identifiers

PMID33404362
PMCPMC7924513

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.