ArticleEnvironmental health perspectives2021
Lifetime Pesticide Use and Monoclonal Gammopathy of Undetermined Significance in a Prospective Cohort of Male Farmers.
Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Unequal harvests: AI-assisted evidence map of trends and gaps in global farmer health research along SDG 3 priorities.BMJ open · 2026Review
- MGUS prevalence among active-duty military personnel.Blood cancer journal · 2026Article
- Organochlorine pesticide use and mosaic loss of chromosome Y in a study of male farmers.Environmental research · 2025Article
- Screening for monoclonal gammopathies of undetermined significance: A prospective study.Journal of public health in Africa · 2025Article
- Quantitative measures of recent and lifetime agricultural pesticide use are associated with increased pesticide concentrations in house dust.Environment international · 2024Article
- Article
- Multiple Myeloma and Occupational Risk Factors: A Narrative Review.Iranian journal of public health · 2024Review
- Dietary risk factors for monoclonal gammopathy of undetermined significance in a racially diverse population.Blood advances · 2024Article
- Review
- Geospatial analysis of population-based incidence of multiple myeloma in the United States.Cancer epidemiology · 2023Article
- Occupational exposure to pesticides dysregulates systemic Th1/Th2/Th17 cytokines and correlates with poor clinical outcomes in breast cancer patients.Frontiers in immunology · 2023Article
- Monitoring residues of pesticides in food in Brazil: A multiscale analysis of the main contaminants, dietary cancer risk estimative and mechanisms associated.Frontiers in public health · 2023Article
- Invited Perspective: Pesticide Adjuvants and Inert Ingredients - A Missing Piece of the Puzzle.Environmental health perspectives · 2022Article
- Epidemiology, genetics and treatment of multiple myeloma and precursor diseases.International journal of cancer · 2021Review
- Pesticide use and kidney function among farmers in the Biomarkers of Exposure and Effect in Agriculture study.Environmental research · 2021Article
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundFarmers have a higher incidence of multiple myeloma, and there is suggestive evidence of an elevated prevalence of its precursor, monoclonal gammopathy of undetermined significance (MGUS), relative to the general population. Pesticide exposures are suspected to play a role; however, the biologic plausibility for associations with multiple myeloma remains unclear.
objectivesOur objectives were to examine the prevalence of MGUS and evaluate associations with a wide range of pesticides in a large sample of farmers.
methodsWe obtained sera and assessed MGUS among 1,638 male farmers
resultsThe age-standardized MGUS prevalence was significantly elevated among AHS farmers (7.7%) compared with demographically similar men in the National Health and Nutrition Examination Survey (2.8%) or Olmsted County, Minnesota (3.8%; DISCUSSION: This is the largest investigation of MGUS in farmers and the first to identify an association with MGUS for permethrin, a pyrethroid insecticide previously associated with multiple myeloma. Given the continued widespread use of permethrin in various residential and commercial settings, our findings may have important implications for exposed individuals in the general population. https://doi.org/10.1289/EHP6960.
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