Evidence map›Paper›PMID 33404197›Full record

ArticlePediatric pulmonology2021

Lung ultrasound in the diagnosis and monitoring of 30 children with coronavirus disease 2019.

Anna Maria Musolino, Maria Chiara Supino, Danilo Buonsenso, Raffaele Edo Papa, Sara Chiurchiù, Andrea Magistrelli, Maria Antonietta Barbieri, Massimiliano Raponi, Patrizia D'Argenio, Alberto Villani and 2 more

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Pediatric pulmonology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

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  10. What Is COVID 19 Teaching Us about Pulmonary Ultrasound?Diagnostics (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Anna Maria MusolinoPediatric Emergency, Department of Emergency and General Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.ORCID 0000-0001-9606-2860
Maria Chiara SupinoPediatric Emergency, Department of Emergency and General Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.ORCID 0000-0003-2507-8886
Danilo BuonsensoDepartment of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0001-8567-2639
Raffaele Edo PapaPediatric Unit, Department of Emergency and General Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Palidoro, Italy.
Sara ChiurchiùDivision of Immunology and Infectious Disease, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Andrea MagistrelliDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Maria Antonietta BarbieriPediatric Emergency, Department of Emergency and General Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Palidoro, Italy.
Massimiliano RaponiMedical Direction, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Patrizia D'ArgenioDivision of Immunology and Infectious Disease, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Alberto VillaniDepartment of Emergency and General Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Paolo TomàDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.ORCID 0000-0002-0158-4760
LUS COVID Group
Bambino Gesù Children's Hospital · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe coronavirus disease 2019 (COVID-19) has caused a new global pandemic and is responsible for millions of infections and thousands of deaths in the world. The lung ultrasound (LUS) is a noninvasive and easily repeatable tool and can be carried out by the pediatrician at the bedside of children with a consequent reduction in the risk of transmission of the virus.

objectiveWe hypothesized that ultrasound findings in these patients would (1) be associated with their disease severity and (2) change over time in alignment with clinical outcome.

methodsThe study was made in the emergency department (ED) in a tertiary level pediatric hospital. All patients with swab-confirmed COVID-19 infection were subjected to a LUS within 6 h from admission and after 96 h.

resultsAmong a total of 30 children, 18 (60%) were males, 4 reported exertional dyspnea, and only 1 chest pain. The mean oxygen saturation was 98.8 ± 1.0% in ambient air in the ED and no patient needed oxygen therapy during hospitalization. Children with moderate disease presented more B line (p = .03). After 96 h, we had observed ultrasound abnormality only in 20% of the children. We found a statistically significant reduction in pleural irregularities (30% vs. 16.7; p = .001) and in B lines (50% vs. 20%; p = .008).

conclusionsThe LUS is a useful, feasible, and safe tool for the clinician to complement the clinical evaluation and to monitor the evolution of lung disease in children with COVID-19.

Indexed as

Child, HospitalizedCOVID-19SARS-CoV-2AdolescentChildChild, PreschoolFemaleHumansInfantMalePneumonia, ViralPoint-of-Care TestingPredictive Value of TestsTomography, X-Ray ComputedUltrasonographychildrencoronavirus disease 2019COVID-19lung ultrasoundSARS-CoV2

Identifiers

PMID33404197
OpenAlexW3119180748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.