ArticleBioscience reports2021
Development of next-generation antimicrobial hydrogel dressing to combat burn wound infection.
Article in Bioscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- Development and Characterization of a Silver Nanoparticle-Based Hydrogel Containing Hyaluronic Acid and Allantoin for Antibacterial Burn Treatment.Pharmaceutics · 2026Article
- Therapeutic potential of a pullulan polysaccharide-based hydrogel with antibacterial peptide for skin wound healing.Iranian journal of basic medical sciences · 2026Article
- Synthesis of novel nano composite based on silicone/HEMA/AAm/ZnO as an efficient wound dressing: physicochemical and biological study.Designed monomers and polymers · 2026Article
- Advanced Hydrogel Functionalization Strategies for Burn-Related Wound Treatment.Biomaterials research · 2026Review
- Controlled release of antimicrobial peptides from nanocellulose wound dressings for treatment of wound infections.Materials today. Bio · 2025Article
- Current State and Advances in Antimicrobial Strategies for Burn Wound Dressings: From Metal-Based Antimicrobials and Natural Bioactive Agents to Future Perspectives.International journal of molecular sciences · 2025Review
- Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation.Antibiotics (Basel, Switzerland) · 2024Review
- Shear-Thinning Extrudable Hydrogels Based on Star Polypeptides with Antimicrobial Properties.Gels (Basel, Switzerland) · 2024Article
- Multidrug-Resistant Organisms: The Silent Plight of Burn Patients.Journal of burn care & research : official publication of the American Burn Association · 2024Review
- Dual-Delivery Temperature-Sensitive Hydrogel with Antimicrobial and Anti-Inflammatory Brevilin A and Nitric Oxide for Wound Healing in Bacterial Infection.Gels (Basel, Switzerland) · 2024Article
- Evolutionary andCurrent research in microbial sciences · 2023Article
- Preparation and characterization of 3D-printed antibacterial hydrogel with benzyl isothiocyanate.International journal of bioprinting · 2023Article
- Chemical composition, mineral profile, anti-bacterial, and wound healing properties of snail slime ofBioMedicine · 2023Article
- Evaluating polymeric biomaterials to improve next generation wound dressing design.Biomaterials research · 2022Review
- Hydrogels in Burn Wound Management-A Review.Gels (Basel, Switzerland) · 2022Review
- Treatment of experimentally induced partial-thickness burns in rats with different silver-impregnated dressings.Acta cirurgica brasileira · 2022Article
- Methicillin-resistant Staphylococcus aureus as a cause of chronic wound infections: Alternative strategies for management.AIMS microbiology · 2022Review
- Article
- Antimicrobial efficacy of Egyptian Eremina desertorum and Helix aspersa snail mucus with a novel approach to their anti-inflammatory and wound healing potencies.Scientific reports · 2021Article
- Eradication of Mature Bacterial Biofilms with Concurrent Improvement in Chronic Wound Healing Using Silver Nanoparticle Hydrogel Treatment.Biomedicines · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infection of burn wounds often leads to poor healing, sepsis, disability, or even death. Traditional care focuses on early debridement, fluid resuscitation, and intravenous antibiotics but these are often inadequate due to compromised vasculature limiting systemic antibiotics effectiveness. Biofilms in burn wounds are barriers to treatment and are associated with the transition of wounds from acute to chronic non-healing state. Current topical treatments for burn wounds include skin substitutes impregnated with skin or stem cells that promote healing; or hydrogels delivering an antibiotic, silver, or synthetic antimicrobial peptides. The success of currently available products is varied and, in some cases, very limited due to associated cytotoxicity to mammalian cells, the ability to only fight extracellular biofilm infections, and the ever-increasing development of antimicrobial resistance (AMR). There is, therefore, a high clinical need for the development of next-generation hydrogel wound dressings, to combat bacterial burn wound infection. A recent paper by Khan et al. (Bioscience Reports (2020) 39, https://doi.org/10.1042/BSR20190504) highlights the development of a catechol cross-linked antimicrobial peptide hydrogel, adding to the body of literature describing innovative solutions with better delivery systems for antimicrobial peptides, and identifying a promising future biomaterial for development of novel hydrogel dressing to combat multi-drug resistant bacterial infections in burn wounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.