ArticleBJPsych open2021
Using a simulation centre to evaluate preliminary acceptability and impact of an artificial intelligence-powered clinical decision support system for depression treatment on the physician-patient interaction.
Article in BJPsych open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Barriers and Facilitators to Patient Acceptance of Artificial Intelligence in Health Care: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Trust in Artificial Intelligence-Based Clinical Decision Support Systems Among Health Care Workers: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Integrating Artificial Intelligence (AI) With Workforce Solutions for Sustainable Care: A Follow Up to Artificial Intelligence and Machine Learning (ML) Based Decision Support Systems in Mental Health.International journal of mental health nursing · 2025Pooled it
- Availability of Evidence for Predictive Machine Learning Algorithms in Primary Care: A Systematic Review.JAMA network open · 2024Pooled it
- Inclusion of Clinicians in the Development and Evaluation of Clinical Artificial Intelligence Tools: A Systematic Literature Review.Frontiers in psychology · 2022Pooled it
- AI-Assisted Cardiovascular Risk Assessment by General Practitioners in Resource-Constrained Indonesian Settings Using a Conceptual Prototype: Randomized Controlled Study.Journal of medical Internet research · 2025Trial
- Out with AI, in with the psychiatrist: a preference for human-derived clinical decision support in depression care.Translational psychiatry · 2023Trial
- Participatory Design of AI-Based Clinical Decision Support Systems: Scoping Review.JMIR medical informatics · 2026Article
- Article
- A Systematic Review of Factors Affecting Utilization of Decision Support Systems: The Interplay Between Technology, Users, and the Healthcare Environment.Health science reports · 2026Review
- The Use of Artificial Intelligence for Personalized Treatment in Psychiatry.Current psychiatry reports · 2025Review
- Reimagining healthcare education through nurturing AI-driven innovation.BMC medical education · 2025Review
- Development of the treatment prediction model in the artificial intelligence in depression - medication enhancement study.Npj mental health research · 2025Article
- Barriers to and facilitators of clinician acceptance and use of artificial intelligence in healthcare settings: a scoping review.BMJ open · 2025Article
- The Use of AI in Mental Health Services to Support Decision-Making: Scoping Review.Journal of medical Internet research · 2025Article
- Designing and testing clinical simulations of an early warning system for implementation in acute care settings.JAMIA open · 2024Article
- Quality of interaction between clinicians and artificial intelligence systems. A systematic review.Future healthcare journal · 2024Review
- Development of a differential treatment selection model for depression on consolidated and transformed clinical trial datasets.Translational psychiatry · 2024Article
- Evidence for Reduced Sensory Precision and Increased Reliance on Priors in Hallucination-Prone Individuals in a General Population Sample.Schizophrenia bulletin · 2024Article
- Automation in Contemporary Clinical Information Systems: a Survey of AI in Healthcare Settings.Yearbook of medical informatics · 2023Article
Corrections and comments
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Authors and funding
31 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecently, artificial intelligence-powered devices have been put forward as potentially powerful tools for the improvement of mental healthcare. An important question is how these devices impact the physician-patient interaction.
aimsAifred is an artificial intelligence-powered clinical decision support system (CDSS) for the treatment of major depression. Here, we explore the use of a simulation centre environment in evaluating the usability of Aifred, particularly its impact on the physician-patient interaction.
methodTwenty psychiatry and family medicine attending staff and residents were recruited to complete a 2.5-h study at a clinical interaction simulation centre with standardised patients. Each physician had the option of using the CDSS to inform their treatment choice in three 10-min clinical scenarios with standardised patients portraying mild, moderate and severe episodes of major depression. Feasibility and acceptability data were collected through self-report questionnaires, scenario observations, interviews and standardised patient feedback.
resultsAll 20 participants completed the study. Initial results indicate that the tool was acceptable to clinicians and feasible for use during clinical encounters. Clinicians indicated a willingness to use the tool in real clinical practice, a significant degree of trust in the system's predictions to assist with treatment selection, and reported that the tool helped increase patient understanding of and trust in treatment. The simulation environment allowed for the evaluation of the tool's impact on the physician-patient interaction.
conclusionsThe simulation centre allowed for direct observations of clinician use and impact of the tool on the clinician-patient interaction before clinical studies. It may therefore offer a useful and important environment in the early testing of new technological tools. The present results will inform further tool development and clinician training materials.
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