Evidence map›Paper›PMID 33403907›Full record

ArticlePharmaceutical biology2021

Hepatoprotective effect of

Ernawati Sinaga, Ami Fitrayadi, Asrori Asrori, Sri Endarti Rahayu, Suprihatin Suprihatin, Vivitri Dewi Prasasty

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Hepatoprotective and Nephroprotective Effects ofInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Hepatoprotective and antioxidant effects ofInternational journal of biochemistry and molecular biology · 2025
    Article
  6. Review
  7. Biological Characterization ofAntibiotics (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. The Employment of GeneraNutrients · 2022
    Review
  12. Frontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ernawati SinagaFaculty of Biology, Universitas Nasional, Jakarta, Indonesia.
Ami FitrayadiFaculty of Biology, Universitas Nasional, Jakarta, Indonesia.
Asrori AsroriFaculty of Biology, Universitas Nasional, Jakarta, Indonesia.
Sri Endarti RahayuFaculty of Biology, Universitas Nasional, Jakarta, Indonesia.
Suprihatin SuprihatinFaculty of Biology, Universitas Nasional, Jakarta, Indonesia.
Vivitri Dewi PrasastyFaculty of Biotechnology, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Nasional University · IDAtma Jaya Catholic University of Indonesia · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

context

objectiveTo investigate the hepatoprotection aspect of MATERIALS AND

methodsThirty male Sprague-Dawley rats were randomly divided into six equal groups: one group served as the healthy control and five groups with hepatotoxicity (hepatotoxic control and 4 treatment groups). The oral treatment of paracetamol-induced hepatotoxicity of 3 g/kg using three different concentrations of

resultsDISCUSSION AND

conclusions

Indexed as

PandanaceaeSeedsAcetaminophenAnalgesics, Non-NarcoticAnimalsAntioxidantsChemical and Drug Induced Liver InjuryLiverMalePlant ExtractsRatsRats, Sprague-DawleyRats, WistarTreatment OutcomeAcetaminophenAnalgesics, Non-NarcoticAntioxidantsPlant ExtractsAnti-hepatotoxicityantioxidanthistopathologysilymarin

Identifiers

PMID33403907
PMCPMC7801105
OpenAlexW3120568349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.