ArticleDevelopmental psychobiology2021
Exploring valence bias as a metric for frontoamygdalar connectivity and depressive symptoms in childhood.
Article in Developmental psychobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? - a systematic review.Journal of child psychology and psychiatry, and allied disciplines · 2025Pooled it
- The role of trait reappraisal in response to emotional ambiguity: A systematic review and meta-analysis.Emotion (Washington, D.C.) · 2024Pooled it
- Facing ambiguity: What we do in the space between stimulus and response.Current directions in psychological science · 2026Article
- Multimodal correlates of socioemotional movie-watching and their associations with internalizing symptoms in childhood and adulthood.Social cognitive and affective neuroscience · 2026Article
- Valence bias arises from both positive and negative responses to ambiguous stimuli.Frontiers in psychology · 2026Article
- Spatiotemporal dynamics of multispectral oscillatory activity underlying the processing of negative and positive emotional images.NeuroImage · 2025Article
- Intergenerational Transmission of Valence Bias Is Moderated by Attachment.Developmental science · 2025Article
- Oscillatory brain dynamics underlying affective face processing.Social cognitive and affective neuroscience · 2025Article
- Chronic Stress May Amplify Gender/Sex Differences in Amygdala Reactivity to Ambiguous Emotional Stimuli.Stress and health : journal of the International Society for the Investigation of Stress · 2025Article
- Segregation of three resting-state brain networks predicts reappraisal success across the lifespan.Social cognitive and affective neuroscience · 2025Article
- In the face of ambiguity: intrinsic brain organization in development predicts one's bias toward positivity or negativity.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Resting-state functional network segregation of the default mode network predicts valence bias across the lifespan.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Think again: the role of reappraisal in reducing negative valence bias.Cognition & emotion · 2023Article
- Tendency to Share Positive Emotions Buffers Loneliness-Related Negativity in the Context of Shared Adversity.Journal of research in personality · 2023Article
- Interpersonal emotion regulation mitigates the link between trait neuroticism and a more negative valence bias.Personality and individual differences · 2022Article
- Article
- Positivity effect in aging: evidence for the primacy of positive responses to emotional ambiguity.Neurobiology of aging · 2021Article
- Social connectedness and negative affect uniquely explain individual differences in response to emotional ambiguity.Scientific reports · 2021Article
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3 authors.
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Abstract
Negativity bias is a core feature of depression that is associated with dysfunctional frontoamygdalar connectivity; this pathway is associated with emotion regulation and sensitive to neurobiological change during puberty. We used a valence bias task (ratings of emotional ambiguity) as a potential early indicator of depression risk and differences in frontoamygdalar connectivity. Previous work using this task demonstrated that children normatively have a negative bias that attenuates with maturation. Here, we test the hypothesis that persistence of this negativity bias as maturation ensues may reveal differences in emotion regulation development, and may be associated with increased risk for depression. In children aged 6-13 years, we tested the moderating role of puberty on relationships between valence bias, depressive symptoms, and frontoamygdalar connectivity. A negative bias was associated with increased depressive symptoms for those at more advanced pubertal stages (within this sample) and less regulatory frontoamygdalar connectivity, whereas a more positive bias was associated with more regulatory connectivity patterns. These data suggest that with maturation, individual differences in positivity biases and associated emotion regulation circuitry confer a differential risk for depression. Longitudinal work is necessary to determine the directionality of these effects and explore the influence of early life events.
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