ArticleActa neurochirurgica2021
Utility of intraoperative ultrasonography for resection of pituitary adenomas: a comparative retrospective study.
Article in Acta neurochirurgica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 19 citations in OpenAlex.
- Rebirth of an old modality: revisiting intraoperative ultrasound in pituitary surgery.Pituitary · 2025Article
- Intraoperative Ultrasound in Brain and Spine Surgery: Current Applications, Translational Value and Future Perspectives.NeuroSci · 2025Review
- Challenges and opportunities for new intraoperative optical techniques in the surgical treatment of pituitary adenomas: a review.Journal of biomedical optics · 2025Review
- Development and preclinical evaluation of an endonasal Raman spectroscopy probe for transsphenoidal pituitary adenoma surgery.Journal of biomedical optics · 2025Article
- Neuronavigation-assisted pituitary neuroendocrine tumor resection: a systematic review and meta-analysis.Quantitative imaging in medicine and surgery · 2024Article
- A rare case of double pituitary prolactinomas: the diagnostic application of intraoperative ultrasonography and DNA methylation markers.Archives of endocrinology and metabolism · 2024Article
- Operative Adjuncts in Pediatric Brain Tumor Surgery with a Focus on Suprasellar Tumors.Advances and technical standards in neurosurgery · 2024Review
- Endoscopic ultrasound guided resection of a Cushing's adenoma invading the medial cavernous sinus wall using the "interdural peeling" technique.Neurosurgical focus: Video · 2023Article
- Automatic rigid image Fusion of preoperative MR and intraoperative US acquired after craniotomy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- Case report: Side-firing intraoperative ultrasound guided endoscopic endonasal resection of a clival chordoma.Frontiers in oncology · 2023Article
- The Current State of Visualization Techniques in Endoscopic Skull Base Surgery.Brain sciences · 2022Review
- Side-firing intraoperative ultrasound applied to resection of pituitary macroadenomas and giant adenomas: A single-center retrospective case-control study.Frontiers in oncology · 2022Article
- Current Limitations of Intraoperative Ultrasound in Brain Tumor Surgery.Frontiers in oncology · 2021Review
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4 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe evolution of pituitary surgery has made it a safe and effective form of treatment; however, risks of inadequate tumor resection, cerebrospinal fluid (CSF) leak, pituitary dysfunction, and vascular injury still exist. The use of intraoperative ultrasonography (IOUS) in pituitary surgery has been well described. Recent advancements in ultrasound technology have allowed for expanded utility as described here.
methodsA retrospective review was performed between January 2016 and December 2019. One hundred thirty-eight patients (mean age 53.7 years, 47% females) were identified undergoing transsphenoidal surgery for pituitary tumors. Thirty-four patients had IOUS performed using a side-firing ultrasound probe, while 104 did not. Data was analyzed for preoperative (demographics, clinical, and radiographic features), perioperative (blood loss, operative time), and postoperative (complications, length of stay, hormone remission, and extent of resection) outcomes.
resultsThere were no significant differences in patient age, gender, tumor volume, Knosp grade, and hormone-secreting status between the two groups. Patients treated using IOUS had significantly higher rates of gross total resection (79% vs. 44%, p = 0.0008), shorter operative times (74 vs. 146 min, p < 0.0001), lower blood loss (119 vs. 284 cc, p < 0.0001), and hospital stays (2.9 vs. 4.2 days, p = 0.001). Overall complication rates were lower in the IOUS group compared to standard pituitary surgery but did not reach significance.
conclusionsRecent improvements in ultrasound technology have allowed for miniaturization of probes capable of delivering high-resolution images. The use of IOUS in transsphenoidal pituitary surgery may significantly increase rates of gross total resection, while decreasing blood loss, hospital LOS, and operative time.
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