Evidence map›Paper›PMID 33403219›Full record

ArticleOpen forum infectious diseases2020

Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospital Workers: Results From a Screening Study in New Jersey, United States in Spring 2020.

Emily S Barrett, Daniel B Horton, Jason Roy, Weiyi Xia, Patricia Greenberg, Tracy Andrews, Maria Laura Gennaro, Veenat Parmar, William D Russell, Nancy Reilly and 7 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Age and Hair Cortisol Levels as Predictors of SARS-CoV-2 Infection.International journal of environmental research and public health · 2024
    Article
  5. Article
  6. Socioeconomic and Demographic Risk Factors for SARS-CoV-2 Seropositivity Among Healthcare Workers in a UK Hospital: A Prospective Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Observational
  7. Observational
  8. Article
  9. Article
  10. Connect: Cultivating Academic-Community Partnerships to Address Our Communities' Complex Needs During Public Health Crises.Progress in community health partnerships : research, education, and action · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 2 countries.

Emily S BarrettDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health; Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, New Jersey, USA.ORCID 0000-0001-9463-524X
Daniel B HortonDepartment of Pediatrics, Rutgers Robert Wood Johnson Medical School; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research; Department of Biostatistics and Epidemiology, Rutgers School of Public Health, New Brunswick, New Jersey, USA.
Jason RoyDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey, USA.
Weiyi XiaDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey, USA.
Patricia GreenbergDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey, USA.
Tracy AndrewsDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey, USA.
Maria Laura GennaroPublic Health Research Institute; Department of Medicine, New Jersey Medical School; Rutgers University, Newark, New Jersey, USA.
Veenat ParmarCenter for Advanced Biotechnology and Medicine, Rutgers University; Rutgers University Microbiome Program, Piscataway, New Jersey, USA.
William D RussellRutgers Institute for Translational Medicine and Science, New Brunswick, New Jersey, USA.
Nancy ReillyRutgers Institute for Translational Medicine and Science, New Brunswick, New Jersey, USA.
Priyanka UpretyDepartment of Pathology and Laboratory Medicine, Rutgers Robert Wood Johnson Medical School; Robert Wood Johnson University Hospital, New Brunswick, New Jersey, USA.
John J GantnerRobert Wood Johnson University Hospital, New Brunswick, New Jersey, USA.
Lydia StockmanRobert Wood Johnson University Hospital, New Brunswick, New Jersey, USA.
Stanley Z TrooskinDepartment of Surgery, Rutgers Robert Wood Johnson Medical School; Robert Wood Johnson University Hospital, New Brunswick, New Jersey, USA.
Martin J BlaserCenter for Advanced Biotechnology and Medicine, Rutgers University; Department of Medicine, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Jeffrey L CarsonDepartment of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Reynold A PanettieriRutgers Institute for Translational Medicine and Science; Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Rutgers, The State University of New Jersey · USRobert Wood Johnson University Hospital · US

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI HOWARD M KIPEN · 1988 to 2026
$47.4M
New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
Myocardial Ischemia and Transfusion (MINT) - CCCU01HL133817 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI CARSON, JEFFREY LEE · 2016 to 2022
$17.1M
Microbial, immune, metabolic perturbations by antibiotics (MIME study)U01AI122285 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI MARTIN J BLASER, Steven M Holland · 2016 to 2026
$5.2M
Statins as Adjunctive, Host-Directed Therapy for TBUH3AI122309 · NIAID · JOHNS HOPKINS UNIVERSITY · PI KARAKOUSIS, PETROS C · 2017 to 2019
$4.3M
Foam cells as drug targets in tuberculosisR01HL149450 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GENNARO, MARIA LAURA, KARAKOUSIS, PETROS C · 2019 to 2022
$3.9M
Drugs, Germs, and Joints: Antibiotics, Gut Microbiota, and Juvenile Idiopathic ArthritisK23AR070286 · NIAMS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI HORTON, DANIEL BENJAMIN · 2016 to 2020
$909k
NCATS NIH HHS UL1 TR003017NHLBI NIH HHS R01 HL149450NHLBI NIH HHS U01 HL133817NIAID NIH HHS U01 AI122285NIAID NIH HHS UH3 AI122309NIAMS NIH HHS K23 AR070286NIEHS NIH HHS P30 ES005022
6 · The paper itself

Abstract

backgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a critical concern among healthcare workers (HCWs). Other studies have assessed SARS-CoV-2 virus and antibodies in HCWs, with disparate findings regarding risk based on role and demographics.

methodsWe screened 3904 employees and clinicians for SARS-CoV-2 virus positivity and serum immunoglobulin (Ig)G at a major New Jersey hospital from April 28 to June 30, 2020. We assessed positive tests in relation to demographic and occupational characteristics and prior coronavirus disease 2019 symptoms using multivariable logistic regression models.

resultsThirteen participants (0.3%) tested positive for virus and 374 (9.6%) tested positive for IgG (total positive: 381 [9.8%]). Compared with participants with no patient care duties, the odds of positive testing (virus or antibodies) were higher for those with direct patient contact: below-median patient contact, adjusted odds ratio (aOR) = 1.71 and 95% confidence interval [CI] = 1.18-2.48; above-median patient contact, aOR = 1.98 and 95% CI = 1.35-2.91. The proportion of participants testing positive was highest for phlebotomists (23.9%), maintenance/housekeeping (17.3%), dining/food services (16.9%), and interpersonal/support roles (13.7%) despite lower levels of direct patient care duties. Positivity rates were lower among doctors (7.2%) and nurses (9.1%), roles with fewer underrepresented minorities. After adjusting for job role and patient care responsibilities and other factors, Black and Latinx workers had 2-fold increased odds of a positive test compared with white workers. Loss of smell, taste, and fever were associated with positive testing.

conclusionsThe HCW categories at highest risk for SARS-CoV-2 infection include support staff and underrepresented minorities with and without patient care responsibilities. Future work is needed to examine potential sources of community and nosocomial exposure among these understudied HCWs.

Indexed as

COVID-19disparitieshealthcare workershospital epidemiologySARS-CoV-2

Identifiers

PMID33403219
PMCPMC7665723
OpenAlexW3116313426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.