Evidence map›Paper›PMID 33402911›Full record

ReviewAfrican health sciences2020

A review of the safety of vaccines used in routine immunization in Africa.

Peter Yamoah, Varsha Bangalee, Frasia Oosthuizen

Open access · diamondAbstract readReview
In one paragraph

Review in African health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Peter YamoahSchool of Pharmacy, University of Health and Allied Sciences, Ghana.
Varsha BangaleeCollege of Health Sciences, University of KwaZulu Natal, Durban, South Africa.
Frasia OosthuizenCollege of Health Sciences, University of KwaZulu Natal, Durban, South Africa.
University of KwaZulu-Natal · ZAUniversity of Health and Allied Sciences · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the significant role played by vaccines in global health, concerns over vaccine safety have increased tremendously over the years. There have been occasions where vaccines have caused rare, adverse reactions some of which have led to hospitalizations and even death. It is therefore important to establish the safety profile of routinely used vaccines in order to allay fears pertaining to their use.

objectivesThis review was aimed at pooling together the safety data of selected vaccines used for routine immunization in Africa, a region of the world with paucity of vaccine safety data.

methodsAdverse Events Following Immunization safety data was searched for rotavirus, yellow fever, measles, rubella, tuberculosis (Bacillus Calmette Guerin-BCG), pneumococcal, Haemophilus Influenza type b, polio, meningococcal and the influenza A (H1N1) vaccines in PUBMED, Google Scholar, Clinical trials.gov and Cochrane controlled register of trials databases.

resultsA total of twenty-four serious AEFIs and twenty-three minor AEFIs were identified from the review. The strength of association between AEFIs and vaccine was high for tuberculosis vaccine and moderate for all other vaccines.

conclusionEven though AEFIs (including mild and severe) were identified in the review, all the vaccines studied were generally well tolerated.

Indexed as

ChildChild, PreschoolDiphtheria-Tetanus-Pertussis VaccineHumansImmunizationMeaslesMeasles-Mumps-Rubella VaccineRisk AssessmentVaccinationVaccinesDiphtheria-Tetanus-Pertussis VaccineMeasles-Mumps-Rubella VaccineVaccinesAfricaimmunizationSafety of vaccines

Identifiers

PMID33402911
PMCPMC7750064
OpenAlexW3033742047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.