Observational studyAfrican health sciences2020
Incidence and outcome of gestational trophoblastic disease in lower Egypt.
Observational study in African health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Magnitude and predictors of gestational trophoblastic disease in East Africa: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Electrochemical biosensors: a novel approach for rapid and cost-effective hCG monitoring in gestational trophoblastic tumours.RSC advances · 2026Review
- Epidemiology, Histopathologic Patterns, and Clinical Characteristics of Gestational Trophoblastic Diseases in Ethiopia: A Systematic Review and Meta-Analysis Study.Obstetrics and gynecology international · 2026Review
- Article
- Factors influencing serum hCG negativization timing in gestational trophoblastic neoplasia.American journal of cancer research · 2025Article
- Magnitude and its associated factors of gestational trophoblastic disease in East African countries, systematic review and meta-analysis.Frontiers in oncology · 2025Review
- A Case of Metastatic Vulvar Choriocarcinoma Misdiagnosed as Vulvar Abscess: A Case Report.Case reports in obstetrics and gynecology · 2024Article
- Association between gestational trophoblastic disease (GTD) history and clinical outcomes in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles.Reproductive biology and endocrinology : RB&E · 2022Article
- Reproductive health issues, infections and non-communicable diseases.African health sciences · 2020Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundGestational trophoblastic disease (GTD) defines a spectrum of proliferative disorders of trophoblastic epithelium of the placenta. Incidence, risk factors, and outcome may differ from one country to another.
objectiveTo describe incidence, patient characteristics, treatment modalities, and outcome of GTD at Mansoura University which is a referral center of Lower Egypt.
methodsAn observational prospective study was conducted at the GTD Clinic of Mansoura University. The patients were recruited for 12 months from September 2015 to August 2016. The patients' characteristics, management, and outcome were reported.
resultsWe reported 71 clinically diagnosed GTD cases, 62 of them were histologically confirmed, 58 molar (33 CM and 25 PM) in addition to 4 initially presented GTN cases. Mean age of the studied cases was 26.22 years ± 9.30SD. Mean pre-evacuation hCG was 136170 m.i.u/ml ±175880 SD. Most of the cases diagnosed accidentally after abnormal sonographic findings (53.2%). Rate of progression of CM and PM to GTN was 24.2% and 8%, respectively.
conclusionThe incidence of molar pregnancy and GTN in our locality was estimated to be 13.1 and 3.2 per 1000 live births respectively. We found no significance between CM and PM regarding hCG level, time to hCG normalization, and progression rate to GTN.
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