Evidence map›Paper›PMID 33402822›Full record

ArticleInternational journal of nanomedicine2020

Lethal Mechanisms of

Reham Samir Hamida, Mohamed Abdelaal Ali, Doaa A Goda, Mayasar Ibrahim Al-Zaban

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

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  9. Biosynthesis of silver nanoparticles (Ag-NPs) usingSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Reham Samir HamidaMolecular Biology Unit, Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt.ORCID 0000-0003-2441-6599
Mohamed Abdelaal AliBiotechnology Unit, Department of Plant Production, College of Food and Agriculture Science, King Saud University, Riyadh, Saudi Arabia.
Doaa A GodaBioprocess Development Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.
Mayasar Ibrahim Al-ZabanDepartment of Biology, College of Science Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Alexandria University · EGCity of Scientific Research and Technological Applications · EGKing Saud University · SAPrincess Nourah bint Abdulrahman University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreasing antibiotic resistance and the emergence of multidrug-resistant (MDR) pathogens have led to the need to develop new therapeutic agents to tackle microbial infections. Nano-antibiotics are a novel generation of nanomaterials with significant antimicrobial activities that target bacterial defense systems including biofilm formation, membrane permeability, and virulence activity. PURPOSE: In addition to AgNO

methodsPotential mechanisms of action of both silver species against bacteria were systematically explored using agar well diffusion, enzyme (lactate dehydrogenase (LDH) and ATPase) and antioxidant (glutathione peroxidase and catalase)   assays, and morphological examinations. qRT-PCR and SDS-PAGE were employed to investigate the effect of both treatments on

resultsN-SNPs exhibited greater biocidal activity than AgNO

conclusionN-SNPs exhibited significant inhibitory potential against

Indexed as

AmpicillinBacteriaCell MembraneEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialHumansMetal NanoparticlesMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsNostocOxidative StressSilverStreptococcus mutansAmpicillinEscherichia coli ProteinsSilverantibacterial activitybiological synthesisnanoparticlesNostoc sp. Bahar_Mpathogenic bacteriasilver

Identifiers

PMID33402822
PMCPMC7778443
OpenAlexW3115369234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.