Evidence map›Paper›PMID 33402563›Full record

ArticleIndian journal of cancer

Evaluating the feasibility of utilizing Gynocular-triage-to-diagnose application with VIA (Visual inspection with Acetic acid) in community cervical cancer screening programs in rural Mysore, India.

Vijaya Srinivas, Holly M Nishimura, Poornima Jayakrishna, Karl Krupp, Purnima Madhivanan, SubbaRao V Madhunapantula

Open access · greenAbstract read
In one paragraph

Article in Indian journal of cancer. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Vijaya SrinivasPublic Health Research Institute of India, Mysore, Karnataka, India.
Holly M NishimuraSchool of Public Health, Johns Hopkins University, Baltimore, Tucson, USA.
Poornima JayakrishnaPublic Health Research Institute of India, Mysore, Karnataka, India.
Karl KruppPublic Health Research Institute of India, Mysore, Karnataka, India; Department Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, Tucson, USA.
Purnima MadhivananDepartment of Medicine, Division of Infectious Diseases; Department of Family & Community Medicine, College of Medicine, University of Arizona, Tucson, USA.
SubbaRao V MadhunapantulaDepartment of Biochemistry, Center of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory, Mysore, Karnataka, India.
Bloomberg (United States) · USUniversity of Arizona · USInstitute for Stem Cell Biology and Regenerative Medicine · INPublic Health Research Institute Of India · IN

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Longitudinal Study of Vaginal Microbiota and Persistent Human Papillomavirus DetectionR15AI128714 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI MADHIVANAN, PURNIMA · 2017 to 2017
$440k
FIC NIH HHS D43 TW010540NIAID NIH HHS R15 AI128714
6 · The paper itself

Abstract

backgroundCervical cancer is the third most common cancer among women in India. The aim of the study is to determine the feasibility of using the Gynocular-triage-to-diagnose (Gynocular T2D/GT2D) in conjunction with visual inspection with acetic acid (VIA) in community-based cervical cancer screening programs in rural Mysore, India.

methodsBetween November 2015 and August 2016, the Public Health Research Institute of India (PHRII) implemented a mobile cervical cancer-screening in Mysore district using VIA and GT2D. Women underwent speculum exams and VIA positive cases were identified. Swede score was assessed using GT2D and a score >4 indicated further monitoring or referral for treatment. Papanicolaou (Pap) smears were conducted for selected cases. Statistical analysis was performed using Chi-square and Fisher's exact tests.

resultsAmong 199 women registered in the camp, 176 were included in the final analysis. 23 women were excluded due to vaginal bleeding. The average age of women was 39 years (range = 27-59 years). Among the 176 cases, 38 (21.6%) were VIA positive and 138 (78.4%) were VIA negative. Swede score of >4 was observed in 6 VIA positive and 7 VIA negative women. Two cases among VIA negative with a score of >4 were suggested biopsy.

conclusionGynocular triaging prevented overtreatment of 32 (18.1%) participants, and identified 7 subjects with >4 Swede score even in VIA negative cases, which would have been ignored if VIA alone was used. In summary, our study demonstrates that Gynocular triaging is feasible in community cervical cancer screening programs.

Indexed as

Acetic AcidAdultEarly Detection of CancerFeasibility StudiesFemaleHumansIndiaUterine Cervical NeoplasmsVaginal SmearsAcetic AcidCervical cancerGynocular T2DPap testswede scoreVIA

Identifiers

PMID33402563
PMCPMC8530208
OpenAlexW3119856437

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.