Evidence map›Paper›PMID 33402533›Full record

ArticlemBio2021

Septal Class A Penicillin-Binding Protein Activity and ld-Transpeptidases Mediate Selection of Colistin-Resistant Lipooligosaccharide-Deficient Acinetobacter baumannii.

Katie N Kang, Misha I Kazi, Jacob Biboy, Joe Gray, Hannah Bovermann, Jessie Ausman, Cara C Boutte, Waldemar Vollmer, Joseph M Boll

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 29 citations in OpenAlex.

  1. LPS in gram-negative bacterial growth and physiology: outside but fully integrated.Microbiology and molecular biology reviews : MMBR · 2026
    Review
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  7. A conserved hub protein required for peptidoglycan remodeling and cell division inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  19. The l,d-Transpeptidase LdtACS infectious diseases · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Katie N KangDepartment of Biology, University of Texas Arlington, Arlington, Texas, USA.ORCID 0000-0003-3026-5360
Misha I KaziDepartment of Biology, University of Texas Arlington, Arlington, Texas, USA.
Jacob BiboyCentre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Joe GrayBiosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Hannah BovermannDepartment of Biology, University of Texas Arlington, Arlington, Texas, USA.
Jessie AusmanDepartment of Biology, University of Texas Arlington, Arlington, Texas, USA.
Cara C BoutteDepartment of Biology, University of Texas Arlington, Arlington, Texas, USA.ORCID 0000-0001-7645-6221
Waldemar VollmerCentre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-0408-8567
Joseph M BollDepartment of Biology, University of Texas Arlington, Arlington, Texas, USA joseph.boll@uta.edu.ORCID 0000-0003-1412-9780
The University of Texas at Arlington · USNewcastle University · GB

Funding

Environmental regulation of cell growth and division in mycobacteriaR15GM131317 · NIGMS · UNIVERSITY OF TEXAS ARLINGTON · PI BOUTTE, CARA CHENEY · 2018 to 2018
$444k
Solving a Multidrug Resistance Puzzle: Complete Loss of LipooligosaccharideR21AI146829 · NIAID · UNIVERSITY OF TEXAS ARLINGTON · PI BOLL, JOSEPH MICHAEL · 2019 to 2020
$391k
NIAID NIH HHS R21 AI146829NIGMS NIH HHS R15 GM131317
6 · The paper itself

Abstract

Despite dogma suggesting that lipopolysaccharide/lipooligosaccharide (LOS) was essential for viability of Gram-negative bacteria, several

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBacterial ProteinsCell MembraneColistinDrug Resistance, Multiple, BacterialGene Expression Regulation, BacterialHumansLipid ALipopolysaccharidesMicrobial Sensitivity TestsPenicillin-Binding ProteinsPeptidoglycan GlycosyltransferasePeptidyl TransferasesAnti-Bacterial AgentsBacterial ProteinsColistinLipid Alipid-linked oligosaccharidesLipopolysaccharidesPenicillin-Binding ProteinsPeptidoglycan GlycosyltransferasePeptidyl TransferasesAcinetobacterGram-negativeld-transpeptidaselipooligosaccharidepenicillin-binding protein 1Apeptidoglycanseptation

Identifiers

PMID33402533
PMCPMC8545086
OpenAlexW3118955386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.