Evidence map›Paper›PMID 33402521›Full record

ArticleIn vivo (Athens, Greece)

The Impact of Peripheral Eosinophil Counts and Eosinophil to Lymphocyte Ratio (ELR) in the Clinical Course of COVID-19 Patients: A Retrospective Study.

Vasiliki E Georgakopoulou, Nikolaos Garmpis, Christos Damaskos, Serena Valsami, Dimitrios Dimitroulis, Evangelos Diamantis, Paraskevi Farmaki, Chrysovalantis V Papageorgiou, Sotiria Makrodimitri, Nikolaos Gravvanis and 18 more

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
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  13. Emerging Evidence for Pleiotropism of Eosinophils.International journal of molecular sciences · 2021
    Review
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Vasiliki E GeorgakopoulouDepartment of Pulmonology, Laiko General Hospital, Athens, Greece.
Nikolaos GarmpisSecond Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Christos DamaskosN.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece; x_damaskos@yahoo.gr.
Serena ValsamiBlood Transfusion Department, Aretaieion Hospital, Medical School, National and Kapodistrian Athens University, Athens, Greece.
Dimitrios DimitroulisSecond Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Evangelos DiamantisDepartment of Endocrinology and Diabetes Center, G. Gennimatas General Hospital, Athens, Greece.
Paraskevi FarmakiFirst Department of Pediatrics, Agia Sofia Children's Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Chrysovalantis V PapageorgiouDepartment of Pulmonology, Laiko General Hospital, Athens, Greece.
Sotiria MakrodimitriDepartment of Pulmonology, Laiko General Hospital, Athens, Greece.
Nikolaos GravvanisHealth Center Peristeriou, Peristeri, Greece.
Stamatis VeloniasHealth Center Peristeriou, Peristeri, Greece.
Pagona SklapaniDepartment of Cytology, Mitera-Hygeia Hospital, Athens, Greece.
Nikolaos TrakasBiochemistry Department, Sismanogleio Hospital, Athens, Greece.
Efstathios A AntoniouSecond Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos KontzoglouSecond Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Lampros NikolidakisDepartment of Internal Medicine, Ygeias Melathron Hospital, Athens, Greece.
Zoi DamaskouDepartment of Internal Medicine, Ygeias Melathron Hospital, Athens, Greece.
Athanasios SyllaiosFirst Department of Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Georgios MarinosEmergency Department, Laiko General Hospital, Athens, Greece.
Georgia VogiatziEmergency Department, Laiko General Hospital, Athens, Greece.
Georgia-Eleni KorrouEmergency Department, Laiko General Hospital, Athens, Greece.
Georgios KyriakosSeccion de Endocrinologia y Nutrition, Hospital General Universitario Santa Lucia, Cartagena, Spain.
Lourdes-Victoria Quiles-SanchezCentro de Salud Jesús Marín, Murcia, Spain.
Alexandros PatsourasSecond Department of Internal Medicine, Tzanio General Hospital, Piraeus, Greece.
Dimitrios LamprinosEmergency Department, Laiko General Hospital, Athens, Greece.
Athanasia StelianidiFirst Department of Pediatrics, Agia Sofia Children's Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Spyridon SavvanisDepartment of Internal Medicine, Elpis General Hospital, Athens, Greece.
Anna GarmpiFirst Department of Propedeutic Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimEosinophils are blood cells responsible for response against parasites and allergens. Eosinophil to lymphocyte ratio (ELR) is a biomarker for inflammatory conditions. Our aim was to evaluate the role of eosinophils and ELR in COVID-19 patients. PATIENTS AND

methodsThe study included 96 patients hospitalized with COVID-19. They were classified into moderate to severe cases and critical cases. Eosinophils and ELR were determined in both groups, in patients that died or survived and were correlated to duration of hospitalization.

resultsThere was a statistically significant decrease in eosinophils and ELR between patients that died and patients that survived (p<0.05), and in mean values of the two biomarkers (p<0.05 for eosinophils and p<0.05 for ELR) between patients hospitalized for more or less than 15 days among those with moderate to severe disease.

conclusionLower eosinophil counts and ERL could probably predict worse outcome in COVID-19 patients.

Indexed as

EosinophilsLymphocytesAdultAgedBiomarkersCOVID-19FemaleHumansLength of StayLeukocyte CountMaleMiddle AgedPrognosisRetrospective StudiesSARS-CoV-2Sensitivity and SpecificityBiomarkersbiomarkerCOVID-19Eosinophilslymphocytepredictionratio

Identifiers

PMID33402521
PMCPMC7880766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.