Evidence map›Paper›PMID 33402469›Full record

ArticleIn vivo (Athens, Greece)

Sulfite Oxidase Is a Novel Prognostic Biomarker of Advanced Gastric Cancer.

Yuta Yano, Jun Akiba, Yoshiki Naito, Eiji Sadashima, Haruhiko Cho, Tsunekazu Hishima, Hirohisa Yano

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Emerging roles of hydrogen sulfide-metabolizing enzymes in cancer.Redox report : communications in free radical research · 2024
    Review
  3. Frontiers in molecular biosciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yuta YanoDepartment of Pathology, Kurume University School of Medicine, Fukuoka, Japan.
Jun AkibaDepartment of Diagnostic Pathology, Kurume University Hospital, Fukuoka, Japan; akiba@med.kurume-u.ac.jp.
Yoshiki NaitoDepartment of Diagnostic Pathology, Kurume University Hospital, Fukuoka, Japan.
Eiji SadashimaLife Science Research Institute, Saga-ken Medical Centre Koseikan, Saga, Japan.
Haruhiko ChoDepartment of Surgery, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan.
Tsunekazu HishimaDepartment of Pathology, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan.
Hirohisa YanoDepartment of Pathology, Kurume University School of Medicine, Fukuoka, Japan.
Kurume University · JPKurume University Hospital · JPTokyo Metropolitan Komagome Hospital · JPSaga-Ken Medical Centre Koseikan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimSulfite oxidase (SUOX) is an enzyme present in the mitochondria, which has been demonstrated to be correlated with various malignant tumours. MATERIALS AND

methodsWe evaluated SUOX expression in tissues of 98 cases of advanced gastric cancer and performed a clinicopathological assessment for metrics.

resultsAmong 98 cases, 55 cases were classified into the SUOX low expression group, and 43 cases into the SUOX high expression group. There were more pStage IV cases in the low expression group. The median overall survival of the low expression group was shorter than that of the high expression group (p=0.020). In univariate and multivariate analysis, SUOX low expression level (p=0.039) and pStage (p<0.001) were independent prognostic factors.

conclusionSUOX is an independent prognostic factor. Therefore, SUOX expression could also serve as a useful marker for elucidating the mechanism of gastric cancer proliferation and progression.

Indexed as

Stomach NeoplasmsSulfite OxidaseBiomarkersBiomarkers, TumorHumansPrognosisBiomarkersBiomarkers, TumorSulfite OxidaseGastric cancerimmunohistochemistryprognosissulfite oxidase

Identifiers

PMID33402469
PMCPMC7880800
OpenAlexW3119826447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.