Evidence map›Paper›PMID 33402446›Full record

SynthesisIn vivo (Athens, Greece)

Sensitivity, Specificity and the Diagnostic Accuracy of PET/CT for Axillary Staging in Patients With Stage I-III Cancer: A Systematic Review of The Literature.

Judi Kasem, Umar Wazir, Kefah Mokbel

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Diagnostic performance ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. The Role of PET/CT in Breast Cancer.Diagnostics (Basel, Switzerland) · 2023
    Review
  15. Review
  16. Review
  17. Article
  18. Escalating de-escalation in breast cancer treatment.Breast cancer research and treatment · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Judi KasemLondon Breast Institute, Princess Grace Hospital, London, U.K.
Umar WazirLondon Breast Institute, Princess Grace Hospital, London, U.K.
Kefah MokbelLondon Breast Institute, Princess Grace Hospital, London, U.K.; kefah.mokbel@hotmail.com.
Khyber Teaching Hospital · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAxillary lymph node (ALN) status plays a key role in the staging of breast cancer. Positron Emission Tomography/Computed Tomography (PET/CT) using 18-Fluorodeoxyglucose ( MATERIALS AND

methodsPubMed, Ovid and Cochrane were searched systematically up until August 2020. Included papers had true positive (TP), false positive (FP), true negative (TN) and false negative (FN) rates, sensitivity, specificity, accuracy, positive (PPV) and negative predictive value (NPV).

resultsNine studies (n=1486) were included, showing: i) sensitivity=52.2%, ii) specificity=91.6%, iii) PPV=77.8%, iv) NPV=77.2, and v) accuracy=77.3%.

conclusion

Indexed as

Breast NeoplasmsPositron Emission Tomography Computed TomographyFemaleFluorodeoxyglucose F18HumansLymphatic MetastasisNeoplasm StagingPositron-Emission TomographyProspective StudiesRadiopharmaceuticalsSensitivity and SpecificityTomography, X-Ray ComputedFluorodeoxyglucose F18Radiopharmaceuticalsaxillary diseaseBreast cancerCT/PETimagingsentinel node biopsy

Identifiers

PMID33402446
PMCPMC7880779
OpenAlexW3118518505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.