Evidence map›Paper›PMID 33402443›Full record

ArticleRMD open2021

Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry.

Bente Glintborg, Dorte Vendelbo Jensen, Sara Engel, Lene Terslev, Mogens Pfeiffer Jensen, Oliver Hendricks, Mikkel Ostergaard, Simon Horskjær Rasmussen, Thomas Adelsten, Ada Colic and 11 more

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 1 country.

Bente GlintborgDANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopedics, Rigshospitalet Glostrup, Glostrup, Denmark glintborg@dadlnet.dk.ORCID 0000-0002-8931-8482
Dorte Vendelbo JensenDANBIO, Rigshospitalet Glostrup, Glostrup, Denmark.
Sara EngelDANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopedics, Rigshospitalet Glostrup, Glostrup, Denmark.
Lene TerslevDepartment of Clinical Medicine, University of Copenhagen Faculty of Health and Medical Sciences, Copenhagen, Denmark.ORCID 0000-0001-8193-9471
Mogens Pfeiffer JensenDepartment of Clinical Medicine, University of Copenhagen Faculty of Health and Medical Sciences, Copenhagen, Denmark.
Oliver HendricksDanish Hospital for Rheumatic Diseases, University of Southern Denmark, Sønderborg, Syddanmark, Denmark.
Mikkel OstergaardDANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopedics, Rigshospitalet Glostrup, Glostrup, Denmark.
Simon Horskjær RasmussenCopenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopedics, Rigshospitalet Glostrup, Glostrup, Denmark.
Thomas AdelstenDepartment of Rheumatology, Sjællands Universitetshospital Køge, Koge, Sjælland, Denmark.
Ada ColicDepartment of Rheumatology, Sjællands Universitetshospital Køge, Koge, Sjælland, Denmark.
Kamilla DanebodCopenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopedics, Rigshospitalet Glostrup, Glostrup, Denmark.
Malene KildemandDepartment of Rheumatology, Odense University Hospital, Odense, Denmark.
Anne Gitte LoftDepartment of Rheumatology, Aarhus University Hospital, Aarhus, Denmark.
Heidi Lausten MunkDepartment of Rheumatology, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-2212-6283
Jens Kristian PedersenDepartment of Medicine, Svendborg Hospital, Svendborg, Syddanmark, Denmark.
René Drage ØstgårdDiagnostic Center, Silkeborg Regional Hospital, Silkeborg, Midtjylland, Denmark.
Christian Møller SørensenDepartment of Medicine, Regional Hospital Horsens, Horsens, Midtjylland, Denmark.
Niels Steen KroghZitelab Aps, Copenhagen, Denmark.
Jette AgerboDanish Rheumatism Association/Gigtforeningen, Copenhagen, Denmark.
Connie ZieglerDanish Rheumatism Association/Gigtforeningen, Copenhagen, Denmark.
Merete HetlandDANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopedics, Rigshospitalet Glostrup, Glostrup, Denmark.ORCID 0000-0003-4229-6818
University of Copenhagen · DKGlostrup Hospital · DKGigtforeningen · DKUniversity of Southern Denmark · DKZealand University Hospital · DKAarhus University · DKOdense University Hospital · DKRegional Hospital Horsens · DKRegionshospitalet Silkeborg · DKSvendborg Sygehus · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsIn Danish patients with inflammatory rheumatic diseases to explore self-protection strategies and health behaviour including adherence to disease-modifying antirheumatic treatment (DMARD) during the initial phase of the COVID-19 pandemic and again after the reopening of the society started. Furthermore, to identify characteristics of patients with high levels of anxiety and self-isolation.

methodsPatients in routine care followed prospectively in the nationwide DANBIO registry were invited to answer an online questionnaire regarding disease activity and COVID-19 infection, behaviour in March and June 2020. Responses were linked to patient data in DANBIO. Characteristics potentially associated with anxiety, self-isolation and medication adherence (gender/age/diagnosis/education/work status/comorbidity/DMARD/smoking/EQ-5D/disease activity) were explored with multivariable logistic regression analyses.

resultsWe included 12 789 patients (8168 rheumatoid arthritis/2068 psoriatic arthritis/1758 axial spondyloarthritis/795 other) of whom 65% were women and 36% treated with biological DMARD. Self-reported COVID-19 prevalence was 0.3%. Patients reported that they were worried to get COVID-19 infection (March/June: 70%/45%) and self-isolated more than others of the same age (48%/38%). The fraction of patients who changed medication due to fear of COVID-19 were 4.1%/0.6%. Female gender, comorbidities, not working, lower education, biological treatment and poor European Quality of life, 5 dimensions were associated with both anxiety and self-isolation.

conclusionIn >12 000 patients with inflammatory arthritis, we found widespread anxiety and self-isolation, but high medication adherence, in the initial phase of the COVID-19 pandemic. This persisted during the gradual opening of society during the following months. Attention to patients' anxiety and self-isolation is important during this and potential future epidemics.

Indexed as

Health BehaviorPandemicsSARS-CoV-2AdultAgedAged, 80 and overAntirheumatic AgentsAnxietyArthritis, PsoriaticArthritis, RheumatoidCOVID-19DenmarkDrug MonitoringFemaleHealth SurveysHumansAntirheumatic Agentsarthritisepidemiologyhealth careoutcome assessmentpatient reported outcome measuresrheumatoid

Identifiers

PMID33402443
PMCPMC7786545
OpenAlexW3118705990

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.