ArticleBMJ open2021
Association between obesity and urinary albumin-creatinine ratio in the middle-aged and elderly population of Southern and Northern China: a cross-sectional study.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of the Association Between Obesity and Albuminuria in Asian People.International journal of hypertension · 2026Review
- Article
- Association between adiposity indices and incident albuminuria: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).BMC nephrology · 2025Article
- Weight-adjusted-waist index is associated with urinary albumin-creatinine ratio in normal body mass index adults: a cross-sectional study from NHANES 2001-2018.Scientific reports · 2025Article
- Review
- Exploring Adiposity and Chronic Kidney Disease: Clinical Implications, Management Strategies, Prognostic Considerations.Medicina (Kaunas, Lithuania) · 2024Review
- Remnant cholesterol is more positively related to diabetes, prediabetes, and insulin resistance than conventional lipid parameters and lipid ratios: A multicenter, large sample survey.Journal of diabetes · 2024Article
- Body mass index modifies the effect of urinary protein-to-creatinine ratio on chronic kidney disease progression.International urology and nephrology · 2024Article
- The Fat Kidney.Current obesity reports · 2023Review
- Association Between Chinese Visceral Adipose Index and Albuminuria in Chinese Adults: A Cross-Sectional Study.International journal of general medicine · 2023Article
- Article
- Association of remnant cholesterol with chronic kidney disease in middle-aged and elderly Chinese: a population-based study.Acta diabetologica · 2021Article
- Association of lipid accumulation product with chronic kidney disease in Chinese community adults: a report from the REACTION study.Lipids in health and disease · 2021Article
- Metabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study.Frontiers in medicine · 2021Article
- Association of Body Composition-Related Indicators with Urinary Protein Levels and Proteinuria Remission in Patients with Primary Membranous Nephropathy.Kidney diseases (Basel, Switzerland)Article
Corrections and comments
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Authors and funding
13 authors at 10 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe relationship between obesity and albuminuria has not been clarified. This study aimed to investigate the correlation between obesity and the urinary albumin-creatinine ratio (UACR) in Southern and Northern China.
designA descriptive, cross-sectional study.
settingEight regional centres in REACTION (China's Risk Evaluation of cAncers in Chinese diabeTic Individuals, a lONgitudinal study), including Dalian, Lanzhou, Zhengzhou, Guangzhou, Guangxi, Luzhou, Shanghai and Wuhan.
participantsA total of 41 085 patients who were not diagnosed with chronic kidney disease (CKD) and had good compliance were selected according to the inclusion criteria. Patients who were diagnosed with CKD, who had other kidney diseases that could lead to increased urinary protein excretion, who were using angiotensin-converting-enzyme inhibitors or angiotensin II receptor blockers and whose important data were missing were excluded.
resultsParticipants with both, central and peripheral obesity, had a higher risk of elevated UACR, even after adjusting for multiple factors (OR: 1.14, 95% CI: 1.07 to 1.12, p<0.001), and the risk of high UACR in the South was more prominent than that in the North (OR
conclusionsIn China, people with both central and peripheral obesity are prone to a high UACR, and the southern population has a higher risk than northern population. Factors such as male sex, hypertension, HbA1c≥6.5% and an age ≥60 years are also risk factors for CKD.
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