Evidence map›Paper›PMID 33402122›Full record

ArticleBMC cancer2021

The surgical treatment of non-metastatic melanoma in a Clinical National Melanoma Registry Study Group (CNMR): a retrospective cohort quality improvement study to reduce the morbidity rates.

Antonella Vecchiato, Simone Mocellin, Paolo Del Fiore, Giulio Tosti, Paolo A Ascierto, Maria Teresa Corradin, Vincenzo De Giorgi, Giuseppe Giudice, Paola Queirolo, Caterina Ferreli and 12 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 1 country.

Antonella VecchiatoSurgical Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padova, Italy.
Simone MocellinSurgical Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padova, Italy.
Paolo Del FioreSurgical Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padova, Italy. paolo.delfiore@iov.veneto.it.ORCID http://orcid.org/0000-0002-2862-8014
Giulio TostiDivision of Melanoma, Sarcoma and Rare Tumors, IRCCS, European Institute of Oncology, Milan, Italy.
Paolo A AsciertoDepartment of Melanoma and Cancer Immunotherapy, Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
Maria Teresa CorradinDepartment of Dermatology, Santa Maria degli Angeli Hospital, Pordenone, Italy.
Vincenzo De GiorgiSection of Dermatology, Department of Health Sciences, University of Florence, Florence, Italy.
Giuseppe GiudiceDivision of Plastic and Reconstructive Surgery and Burn Unit, University of Bari, Bari, Italy.
Paola QueiroloDivision of Medical Oncology for Melanoma, Sarcoma, and Rare Tumors, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Caterina FerreliSection of Dermatology, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Marcella OccelliMedical Oncology Unit, Santa Croce and Carle Teaching Hospital, Cuneo, Italy.
Monica GiordanoPathology, ASST-Lariana, Ospedale Sant'Anna, Como, Italy.
Giusto TrevisanDSM-Department of Medical Sciences, University of Trieste, Trieste, Italy.
Luigi MascheroniUnit of General Surgery, San Pio X Hospital, Milan, Italy.
Alessandro TestoriDepartment of Dermatology, Fondazione IRCCS Policlinico San Matteo, 27100, Pavia, Italy.
Romina SpinaSurgical Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padova, Italy.
Alessandra BujaDepartment of Cardiological, Thoracic and Vascular Sciences, and Public Health, University of Padova, Padova, Italy.
Francesco CavallinIndependent Statistician, Solagna, Italy.
Corrado CaracòNational Cancer Institute Fondazione G. Pascale, SC Chirurgia Melanoma e dei Tumori Cutanei, Naples, Italy.
Antonio SommarivaUnit of Surgical Oncology of the Esophagus and Digestive Tract, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Carlo Riccardo RossiSurgical Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padova, Italy.
Clinical National Melanoma Registry Study Group at the Italian Melanoma Intergroup (IMI)
Istituto Oncologico Veneto · ITUniversity of Padua · ITEuropean Institute of Oncology · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITAzienda Ospedaliera Santa Maria Degli Angeli · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITAzienda Socio Sanitaria Territoriale Lariana · ITIstituto Nazionale di Statistica · ITPoliclinico San Matteo Fondazione · ITUniversity of Bari Aldo Moro · ITUniversity of Cagliari · ITUniversity of Florence · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReproducible, high-quality surgery is a key point in the management of cancer patients. Quality indicators for surgical treatment of melanoma has been presented with benchmarks but data on morbidity are still limited. This study presents the quality indicators on morbidity after surgical treatment for non-metastatic skin melanoma in an Italian registry.

methodsData were extracted from the Central National Melanoma Registry (CNMR) promoted by the Italian Melanoma Intergroup (IMI). All surgical procedures (WE, SNLB or LFND) for non-metastatic skin melanoma between January 2011 and February 2017 were evaluated for inclusion in the study. Only centers with adequate completeness of information (> 80%) were included in the study. Short-term complications (wound infection, dehiscence, skin graft failure and seroma) were investigated.

resultsWound infection rate was 1.1% (0.4 to 2.7%) in WE, 1.3% (0.7 to 2.5%) in SLNB and 4.1% (2.1 to 8.0%) in LFND. Wound dehiscence rate was 2.0% (0.8 to 5.1%) in WE, 0.9% (0.2 to 3.0%) in SLNB and 2.8% (0.9 to 8.6%) in LFND. Seroma rate was 4.2% (1.5 to 11.1%) in SLNB and 15.1% (4.6 to 39.9%) in LFND. Unreliable information was found on skin graft failure.

conclusionsOur findings contribute to available literature in setting up the recommended standards for melanoma centers, thus improving the quality of surgery offered to patients. A consensus on the core issues around surgical morbidity is needed to provide practical guidance on morbidity prevention and management.

Indexed as

Quality ImprovementAgedFemaleFollow-Up StudiesHumansItalyLymph Node ExcisionMaleMelanomaMiddle AgedMorbidityPrognosisProspective StudiesRegistriesRetrospective StudiesSentinel Lymph Node BiopsyMelanomaMelanoma morbidityMelanoma quality improvementMelanoma surgical treatmentSkin Cancer

Identifiers

PMID33402122
PMCPMC7786513
OpenAlexW3109175772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.