Evidence map›Paper›PMID 33401993›Full record

ArticleOpen biology2021

Temperature modulates immune gene expression in mosquitoes during arbovirus infection.

B M C Randika Wimalasiri-Yapa, Roberto A Barrero, Liesel Stassen, Louise M Hafner, Elizabeth A McGraw, Alyssa T Pyke, Cassie C Jansen, Andreas Suhrbier, Laith Yakob, Wenbiao Hu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. The Effect of Increased Temperature on Dengue Virus in the VectorTropical medicine and infectious disease · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Thermal adaptation inProceedings. Biological sciences · 2025
    Article
  8. Article
  9. Insect immunity in the Anthropocene.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Climate change, malaria and neglected tropical diseases: a scoping review.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

B M C Randika Wimalasiri-YapaInstitute of Health and Biomedical Innovation, and School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Roberto A BarreroeResearch Office, Division of Research and Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Liesel StassenInstitute of Health and Biomedical Innovation, and School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Louise M HafnerInstitute of Health and Biomedical Innovation, and School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Elizabeth A McGrawCenter for Infectious Disease Dynamics, Department of Entomology, The Pennsylvania State University, University Park, PA 16801, USA.
Alyssa T PykePublic Health Virology Laboratory, Forensic and Scientific Services, Coopers Plains, Queensland, Australia.
Cassie C JansenCommunicable Diseases Branch, Department of Health, Queensland Government, Herston, Queensland, Australia.
Andreas SuhrbierInflammation Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.
Laith YakobLondon School of Hygiene and Tropical Medicine, London, UK.
Wenbiao HuSchool of Public Health and Social Work, Queensland University of Technology, Brisbane, Queensland, Australia.
Gregor J DevineMosquito Control Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Francesca D FrentiuInstitute of Health and Biomedical Innovation, and School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Queensland University of Technology · AUQueensland Health · AUPennsylvania State University · USQIMR Berghofer Medical Research Institute · AUThe University of Queensland · AUUK Energy Research Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The principal vector of dengue, Zika and chikungunya viruses is the mosquito

Indexed as

AedesAnimalsChikungunya virusDown-RegulationGene OntologyImmunityMosquito VectorsRNA, Long NoncodingSignal TransductionTemperatureUp-RegulationRNA, Long NoncodingAedes aegyptichikungunya virusimmune genesRNA seqtemperaturetranscriptome

Identifiers

PMID33401993
PMCPMC7881175
OpenAlexW3118596391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.