Evidence map›Paper›PMID 33401923›Full record

ArticleCirculation. Arrhythmia and electrophysiology2021

Outcomes of Pediatric Patients With Defibrillators Following Initial Presentation With Sudden Cardiac Arrest.

Jeffrey A Robinson, Martin J LaPage, Joseph Atallah, Gregory Webster, Christina Y Miyake, Christopher Ratnasamy, Nicholas J Ollberding, Shaun Mohan, Nicholas H Von Bergen, Christopher L Johnsrude and 3 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Circulation. Arrhythmia and electrophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Evolution of implantable cardioverter-defibrillator shock therapy in children in the era of optimized ICD programming and remote monitoring.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  3. Review
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  9. The Year in Pediatric Electrophysiology: 2022.The Journal of innovations in cardiac rhythm management · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 2 countries.

Jeffrey A RobinsonThe Heart Institute (J.A.R., D.S.S., R.J.C.), Cincinnati Children's Hospital Medical Center, OH.
Martin J LaPageC.S. Mott Children's Hospital, University of Michigan, Ann Arbor (M.J.L.).
Joseph AtallahDepartment of Pediatrics, University of Alberta, Edmonton, Canada (J.A.).
Gregory WebsterAnn & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, IL (G.W.).
Christina Y MiyakeTexas Children's Hospital, Houston (C.Y.M.).
Christopher RatnasamyCongenital Heart Center, Spectrum Health, Helen DeVos Children's Hospital, Grand Rapids, MI (C.R.).
Nicholas J OllberdingDepartment of Pediatrics, University of Cincinnati College of Medicine, OH (N.J.O.).
Shaun MohanUniversity of Kentucky HealthCare, Lexington (S.M.).
Nicholas H Von BergenAmerican Family Children's Hospital, University of Wisconsin School of Medicine & Public Health, Madison (N.H.V.B.).
Christopher L JohnsrudeUniversity of Louisville, KY (C.L.J.).
Jason M GarnreiterCardinal Glennon Children's Hospital, St. Louis University, MO (J.M.G.).
David S SparThe Heart Institute (J.A.R., D.S.S., R.J.C.), Cincinnati Children's Hospital Medical Center, OH.
Richard J CzosekThe Heart Institute (J.A.R., D.S.S., R.J.C.), Cincinnati Children's Hospital Medical Center, OH.
Cincinnati Children's Hospital Medical Center · USCardinal Glennon Children’s Medical Center · USC. S. Mott Children's Hospital · USHelen DeVos Children's Hospital · USLurie Children's Hospital · USTexas Children's Hospital · USUniversity of Alberta · CAUniversity of Cincinnati Medical Center · USUniversity of Kentucky HealthCare · USUniversity of Louisville · USUniversity of Wisconsin American Family Children's Hospital · US

Funding

Evaluation of First-Degree Relatives after Sudden Unexplained DeathK23HL130554 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI WEBSTER, ROBERT GREGORY · 2017 to 2021
$947k
The Discovery of Novel Genes in Inherited Sudden Arrhythmic Death SyndromesK23HL136932 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI MIYAKE, CHRISTINA YUMI · 2018 to 2022
$888k
NHLBI NIH HHS K23 HL130554NHLBI NIH HHS K23 HL136932
6 · The paper itself

Abstract

backgroundImplantable cardioverter defibrillators (ICD) are recommended for secondary prevention after sudden cardiac arrest (SCA). The outcomes of pediatric patients receiving an ICD after SCA remain unclear. The objective of this study is to evaluate outcomes, future risk for appropriate shocks, and identify characteristics associated with appropriate ICD therapy during follow-up.

methodsMulticenter retrospective analysis of patients (age ≤21 years) without prior cardiac disease who received an ICD following SCA. Patient/device characteristics, cardiac function, and underlying diagnoses were collected, along with SCA event characteristics. Patient outcomes including complications and device therapies were analyzed.

resultsIn total, 106 patients were included, median age 14.7 years. Twenty (19%) received appropriate shocks and 16 (15%) received inappropriate shocks (median follow-up 3 years). First-degree relative with SCA was associated with appropriate shocks (

conclusionsThe risk of future device therapy is high in pediatric patients receiving an ICD after SCA, irrelevant of underlying disease. Lack of a definitive diagnosis after SCA was not associated with lower risk of subsequent events and does not obviate the need for secondary prophylaxis.

Indexed as

Defibrillators, ImplantableAdolescentChildChild, PreschoolDeath, Sudden, CardiacElectric CountershockFemaleHumansIncidenceInfantInfant, NewbornMalePrimary PreventionRetrospective StudiesRisk AssessmentRisk Factorsheart diseaseincidencerisksecondary preventiontachycardia

Identifiers

PMID33401923
PMCPMC7887076
OpenAlexW3119380666

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.