Evidence map›Paper›PMID 33401757›Full record

ArticleInternational journal of environmental research and public health2021

Leading Enterovirus Genotypes Causing Hand, Foot, and Mouth Disease in Guangzhou, China: Relationship with Climate and Vaccination against EV71.

Zhicheng Du, Yong Huang, Wayne R Lawrence, Jianxiong Xu, Zhicong Yang, Jianyun Lu, Zhoubin Zhang, Yuantao Hao

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhicheng DuDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0002-1155-8443
Yong HuangDepartment of Immunization Programme Planning, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Wayne R LawrenceDepartment of Epidemiology and Biostatistics, School of Public Health, State University of New York at Albany, Albany, NY 12144, USA.ORCID 0000-0002-2992-5897
Jianxiong XuDepartment of Immunization Programme Planning, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Zhicong YangDepartment of Communicable Disease Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Jianyun LuDepartment of Communicable Disease Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Zhoubin ZhangDepartment of Communicable Disease Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China.
Yuantao HaoDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0001-8024-5312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Assignment of pathogens to the correct genus, species, and type is vital for controlling infectious epidemics. However, the role of different enteroviruses during hand, foot, and mouth disease (HFMD) epidemics and the major contributing factors remain unknown. (2) Methods: HFMD cases from 2016 to 2018 in Guangzhou, China were collected. The relationship between HFMD cases and genotype frequency, as well as the association between genotype frequency and climate factors, were studied using general linear models. We transformed the genotype frequency to the isometric log-ratio (ILR) components included in the model. Additionally, vaccination rates were adjusted in the climate-driven models. (3) Results: We observed seasonal trends in HFMD cases, genotype frequency, and climate factors. The model regressing case numbers on genotype frequency revealed negative associations with both the ILRs of CAV16 (RR = 0.725,

Indexed as

ClimateChinaEnterovirusEnterovirus InfectionsFemaleGenotypeHand, Foot and Mouth DiseaseHumansLinear ModelsMalePhylogenyPopulation SurveillanceReal-Time Polymerase Chain ReactionReverse Transcriptase Polymerase Chain ReactionVaccinationclimategenotype frequencyhand, foot, and mouth disease

Identifiers

PMID33401757
PMCPMC7795377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.