ReviewBrain sciences2021
Adjunctive Approaches to Aphasia Rehabilitation: A Review on Efficacy and Safety.
Review in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07535788 (Implementing Transcranial Direct Current Stimulation), which is not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Implementing Transcranial Direct Current Stimulation (tDCS) in an Acute Rehabilitation Setting
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Comparative Efficacy of Cognitive Training for Post-Stroke Aphasia: A Systematic Review and Network Meta-Analysis.Neurorehabilitation and neural repair · 2024Pooled it
- Does acupuncture therapy improve language function of patients with aphasia following ischemic stroke? A systematic review and meta-analysis.NeuroRehabilitation · 2022Pooled it
- Revealing the Neuroimaging Mechanism of Acupuncture for Poststroke Aphasia: A Systematic Review.Neural plasticity · 2022Pooled it
- Effect of Acupuncture vs Sham Acupuncture on Patients With Poststroke Motor Aphasia: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Level of discharge readiness and influencing factors in ischaemic stroke patients: a descriptive, cross-sectional study.Frontiers in neurology · 2025Article
- Combining computer-based rehabilitative approach with tDCS for recovering of aphasia: Implications from a single case study.Clinical case reports · 2024Article
- Integration of a large language model with augmentative and alternative communication tool for oncological aphasia rehabilitation.Asia-Pacific journal of oncology nursing · 2024Article
- AI-assisted assessment and treatment of aphasia: a review.Frontiers in public health · 2024Review
- A computer-aid speech rehabilitation system with mirrored video generating.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Ecological Meanings: A Consensus Paper on Individual Differences and Contextual Influences in Embodied Language.Journal of cognition · 2023Article
- Research hotspots and frontiers of post-stroke aphasia rehabilitation: a bibliometric study and visualization analysis.Frontiers in human neuroscience · 2023Article
- Reversing the Ruin: Rehabilitation, Recovery, and Restoration After Stroke.Current neurology and neuroscience reports · 2022Review
- Effects of Acupuncture-Related Therapies in the Rehabilitation of Patients with Post-Stroke Aphasia-A Network Meta-Analysis of Randomized Controlled Trials.Brain sciences · 2022Review
- Review
- Update on Stroke Rehabilitation for Non-Motor Impairment.Brain & NeuroRehabilitation · 2022Review
- Editorial: New Perspectives and Methodologies in the Diagnosis and Rehabilitation of Aphasia.Brain sciences · 2021Article
- Novel Advances to Post-Stroke Aphasia Pharmacology and Rehabilitation.Journal of clinical medicine · 2021Review
- DUAL-tDCS Treatment over the Temporo-Parietal Cortex Enhances Writing Skills: First Evidence from Chronic Post-Stroke Aphasia.Life (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aphasia is one of the most socially disabling post-stroke deficits. Although traditional therapies have been shown to induce adequate clinical improvement, aphasic symptoms often persist. Therefore, unconventional rehabilitation techniques which act as a substitute or as an adjunct to traditional approaches are urgently needed. The present review provides an overview of the efficacy and safety of the principal approaches which have been proposed over the last twenty years. First, we examined the effectiveness of the pharmacological approach, principally used as an adjunct to language therapy, reporting the mechanism of action of each single drug for the recovery of aphasia. Results are conflicting but promising. Secondly, we discussed the application of Virtual Reality (VR) which has been proven to be useful since it potentiates the ecological validity of the language therapy by using virtual contexts which simulate real-life everyday contexts. Finally, we focused on the use of Transcranial Direct Current Stimulation (tDCS), both discussing its applications at the cortical level and highlighting a new perspective, which considers the possibility to extend the use of tDCS over the motor regions. Although the review reveals an extraordinary variability among the different studies, substantial agreement has been reached on some general principles, such as the necessity to consider tDCS only as an adjunct to traditional language therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.