Evidence map›Paper›PMID 33401649›Full record

ArticleMolecules (Basel, Switzerland)2021

Anticancer Activity of Lesbicoumestan in Jurkat Cells via Inhibition of Oxidative Stress-Mediated Apoptosis and MALT1 Protease.

Joo-Eun Lee, Fang Bo, Nguyen Thi Thanh Thuy, Jaewoo Hong, Ji Shin Lee, Namki Cho, Hee Min Yoo

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. The Proteolytic Landscape of Ovarian Cancer: Applications in Nanomedicine.International journal of molecular sciences · 2022
    Review
  4. Biological Activity of Natural and Synthetic Compounds.Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Joo-Eun LeeStem Cell Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.ORCID 0000-0002-2495-1439
Fang BoCollege of Pharmacy, Chonnam National University, Gwangju 61186, Korea.
Nguyen Thi Thanh ThuyCollege of Pharmacy, Chonnam National University, Gwangju 61186, Korea.ORCID 0000-0003-2110-3781
Jaewoo HongDepartment of Physiology, Daegu Catholic University School of Medicine, Daegu 42472, Korea.ORCID 0000-0003-3456-3672
Ji Shin LeeDepartment of Pathology, Chonnam National University Medical School, Gwangju 61469, Korea.ORCID 0000-0003-4634-2228
Namki ChoCollege of Pharmacy, Chonnam National University, Gwangju 61186, Korea.
Hee Min YooBiometrology Group, Korea Research Institute of Standards and Science (KRISS), Daejeon 34113, Korea.ORCID 0000-0002-5951-2137
Chonnam National University · KRChonnam National University Hospital · KRDaegu Catholic University · KRKorea Research Institute of Standards and Science · KR

Funding

Chonnam National University Hwasun Hospital Research Institute of Clinical Medicine HCRI20013Korea Research Institute of Standards and Science KRISS-2020-GP2020-0004National Research Foundation (NRF) of Korea NRF-2018R1C1B5083127
6 · The paper itself

Abstract

This study explores the potential anticancer effects of lesbicoumestan from

Indexed as

Antineoplastic Agents, PhytogenicApoptosisCaspasesCell ProliferationGene Expression Regulation, LeukemicHumansJurkat CellsMitochondriaMolecular Docking SimulationMucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinOxidative StressSpheroids, CellularAntineoplastic Agents, PhytogenicCaspasesMALT1 protein, humanMucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein3D Jurkat celllesbicoumestanMALT1/NF-κBmitochondrial depolarizationROS

Identifiers

PMID33401649
PMCPMC7794876
OpenAlexW3114611022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.