Evidence map›Paper›PMID 33401606›Full record

ArticleHealthcare (Basel, Switzerland)2021

Allergic Rhinitis and Laryngeal Pathology: Real-World Evidence.

Yun-Ting Wang, Geng-He Chang, Yao-Hsu Yang, Chia-Yen Liu, Yao-Te Tsai, Cheng-Ming Hsu, Yi-Chan Lee, Li-Ang Lee, Pei-Rung Yang, Ming-Shao Tsai and 1 more

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Immunological Aspects Allergic Laryngitis: Role of Cellular and Humoral Mechanisms Directing Therapeutic Strategies.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026
    Article
  2. Article
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yun-Ting WangDepartment of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.ORCID 0000-0001-6190-4351
Geng-He ChangDepartment of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.ORCID 0000-0001-5939-9747
Yao-Hsu YangCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-8080-0504
Chia-Yen LiuHealth Information and Epidemiology Laboratory of Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Yao-Te TsaiDepartment of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Cheng-Ming HsuDepartment of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.ORCID 0000-0003-3792-3784
Yi-Chan LeeCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Li-Ang LeeCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0001-8414-595X
Pei-Rung YangCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Ming-Shao TsaiDepartment of Otolaryngology-Head and Neck Surgery, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.ORCID 0000-0002-9314-5940
Hsueh-Yu LiCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chang Gung University · TWChiayi Chang Gung Memorial Hospital · TW

Funding

Chang Gung Memorial Hospital CMRPG6J0331, CMRPG6K0301Taiwan's Ministry of Science and Technology MOST 109-2314-B-182A-054-
6 · The paper itself

Abstract

Allergic rhinitis (AR) is correlated with diseases including allergic laryngitis, chronic obstructive pulmonary disease (COPD), asthma, and chronic rhinosinusitis (CRS). The unified airway model suggests that inflammation can spread in both lower and upper respiratory tracts. Moreover, some voice problems-laryngeal edema, dysphonia, and vocal nodules-have been associated with AR. We examined the association between AR and laryngeal pathology. We investigated 51,618 patients with AR between 1 January 1997 and 31 December 2013, along with 206,472 patients without AR matched based on age, gender, urbanization level, and socioeconomic status at a 1:4 ratio. We followed patients up to the end of 2013 or their death. The occurrence of laryngeal pathology was the primary outcome. Individuals with AR had a 2.43 times higher risk of laryngeal pathology than the comparison cohort group (adjusted HR: 2.43, 95% CI: 2.36-2.50,

Indexed as

Allergic rhinitiscomorbiditieslaryngeal pathologyNHIRDunified airway

Identifiers

PMID33401606
PMCPMC7824592
OpenAlexW3119057633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.