Evidence map›Paper›PMID 33401545›Full record

ArticleInternational journal of molecular sciences2021

Durable Oral Biofilm Resistance of 3D-Printed Dental Base Polymers Containing Zwitterionic Materials.

Jae-Sung Kwon, Ji-Yeong Kim, Utkarsh Mangal, Ji-Young Seo, Myung-Jin Lee, Jie Jin, Jae-Hun Yu, Sung-Hwan Choi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jae-Sung KwonDepartment and Research Institute of Dental Biomaterials and Bioengineering, Yonsei University College of Dentistry, Seoul 03722, Korea.ORCID 0000-0001-9803-7730
Ji-Yeong KimBK21 FOUR Project, Yonsei University College of Dentistry, Seoul 03722, Korea.ORCID 0000-0002-8920-5170
Utkarsh MangalDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of Dentistry, Seoul 03722, Korea.ORCID 0000-0002-8323-9812
Ji-Young SeoDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of Dentistry, Seoul 03722, Korea.ORCID 0000-0003-3895-3117
Myung-Jin LeeDepartment of Dental Hygiene, Division of Health Science, Baekseok University, Cheonan 31065, Korea.
Jie JinDepartment of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of Dentistry, Seoul 03722, Korea.ORCID 0000-0002-5622-0964
Jae-Hun YuBK21 FOUR Project, Yonsei University College of Dentistry, Seoul 03722, Korea.
Sung-Hwan ChoiBK21 FOUR Project, Yonsei University College of Dentistry, Seoul 03722, Korea.ORCID 0000-0002-1150-0268
Yonsei University · KRBaekseok University · KR

Funding

Korea Medical Device Development Fund 202011D04
6 · The paper itself

Abstract

Poly(methyl methacralyate) (PMMA) has long been used in dentistry as a base polymer for dentures, and it is recently being used for the 3D printing of dental materials. Despite its many advantages, its susceptibility to microbial colonization remains to be overcome. In this study, the interface between 3D-printed PMMA specimens and oral salivary biofilm was studied following the addition of zwitterionic materials, 2-methacryloyloxyethyl phosphorylcholine (MPC) or sulfobetaine methacrylate (SB). A significant reduction in bacterial and biofilm adhesions was observed following the addition of MPC or SB, owing to their protein-repellent properties, and there were no significant differences between the two test materials. Although the mechanical properties of the tested materials were degraded, the statistical value of the reduction was minimal and all the properties fulfilled the requirements set by the International Standard, ISO 20795-2. Additionally, both the test materials maintained their resistance to biofilm when subjected to hydrothermal fatigue, with no further deterioration of the mechanical properties. Thus, novel 3D-printable PMMA incorporated with MPC or SB shows durable oral salivary biofilm resistance with maintenance of the physical and mechanical properties.

Indexed as

Bacterial AdhesionBiocompatible MaterialsBiofilmsComposite ResinsDental MaterialsHumansMaterials TestingMethacrylatesMouthPhosphorylcholinePolymersPrinting, Three-DimensionalStreptococcus mutans2-methacryloyloxyethyl phosphorylcholineBiocompatible MaterialsComposite ResinsDental MaterialsMethacrylatesPhosphorylcholinePolymers3D printingdental base resindentistrydurabilityoral salivary biofilmpoly(methyl methacralyate)zwitterion

Identifiers

PMID33401545
PMCPMC7795277
OpenAlexW3120726340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.