ArticlePolymers2021
Protein Unfolding and Aggregation near a Hydrophobic Interface.
Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Spatial Extent and Heterogeneity of Water at Phospholipid Membranes Revealed by Molecular Dynamics.Sub-cellular biochemistry · 2026Review
- Haptens Optimization Using Molecular Modeling and Paper-Based Immunosensor for On-Site Detection of Carbendazim in Vegetable Products.Biosensors · 2025Article
- ExploringACS omega · 2024Article
- Use of a Novel Whole Blood Separation and Transport Device for Targeted and Untargeted Proteomics.Biomedicines · 2024Article
- Genetic Algorithm for Automated Parameterization of Network Hamiltonian Models of Amyloid Fibril Formation.The journal of physical chemistry. B · 2024Article
- Hydrophobic Homopolymer's Coil-Globule Transition and Adsorption onto a Hydrophobic Surface under Different Conditions.The journal of physical chemistry. B · 2023Article
- Article
- Correction: March et al. Protein Unfolding and Aggregation near a Hydrophobic Interface.Polymers · 2023Article
- Enhancing the Conformational Stability of the cl-Par-4 Tumor Suppressor via Site-Directed Mutagenesis.Biomolecules · 2023Article
- Impact of organic solvents on the catalytic performance of halohydrin dehalogenase.Applied microbiology and biotechnology · 2023Article
- Instability Challenges and Stabilization Strategies of Pharmaceutical Proteins.Pharmaceutics · 2022Review
- Amyloidogenesis: What Do We Know So Far?International journal of molecular sciences · 2022Review
- Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes.Nucleic acids research · 2022Article
- Role of Molecular Modification and Protein Folding in the Nucleation and Growth of Protein-Metal-Organic Frameworks.Chemistry of materials : a publication of the American Chemical Society · 2022Article
- Sunset Yellow Dye Induces Amorphous Aggregation in β-Lactoglobulin at Acidic pH: A Multi-Techniques Approach.Polymers · 2022Article
- Advances in the study of supercooled water.The European physical journal. E, Soft matter · 2021Review
- Effect of Tetraphenylborate on Physicochemical Properties of Bovine Serum Albumin.Molecules (Basel, Switzerland) · 2021Article
- Hydration Layer of Only a Few Molecules Controls Lipid Mobility in Biomimetic Membranes.Journal of the American Chemical Society · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
The behavior of proteins near interfaces is relevant for biological and medical purposes. Previous results in bulk show that, when the protein concentration increases, the proteins unfold and, at higher concentrations, aggregate. Here, we study how the presence of a hydrophobic surface affects this course of events. To this goal, we use a coarse-grained model of proteins and study by simulations their folding and aggregation near an ideal hydrophobic surface in an aqueous environment by changing parameters such as temperature and hydrophobic strength, related, e.g., to ions concentration. We show that the hydrophobic surface, as well as the other parameters, affect both the protein unfolding and aggregation. We discuss the interpretation of these results and define future lines for further analysis, with their possible implications in neurodegenerative diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.