Evidence map›Paper›PMID 33401518›Full record

ReviewInternational journal of molecular sciences2021

Melanin-Like Nanomedicine in Photothermal Therapy Applications.

Yale Yue, Xiao Zhao

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Closing the Loop: High-Precision 3D Photofabrication in Living Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. From melanogenesis to melanin technologies.Communications chemistry · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. [Natural melanin-based nanoparticles with photothermal/photodynamic activities induce ovarian cancer cell death].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yale YueSchool of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Xiao ZhaoSchool of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.

Funding

Beijing Natural Science Foundation of China Z200020Beijing Nova Program Z201100006820031Hundred-Talent Program (Chinese Academy of Sciences) 00000000Innovation Research Group of National Natural Science Foundation 11621505Key Research Project of Frontier Science of the Chinese Academy of Sciences QYZDJ-SSW-SLH022National Key R&D Program of China 2018YFA0208900, 2018YFE0205300National Natural Science Foundation of China 31800838, 31820103004, 31730032, 31800799, U190420008 and 31870994
6 · The paper itself

Abstract

Photothermal therapy (PTT) mediated by nanomaterial has become an attractive tumor treatment method due to its obvious advantages. Among various nanomaterials, melanin-like nanoparticles with nature biocompatibility and photothermal conversion properties have attracted more and more attention. Melanin is a natural biological macromolecule widely distributed in the body and displays many fascinating physicochemical properties such as excellent biocompatibility and prominent photothermal conversion ability. Due to the similar properties, Melanin-like nanoparticles have been extensively studied and become promising candidates for clinical application. In this review, we give a comprehensive introduction to the recent advancements of melanin-like nanoparticles in the field of photothermal therapy in the past decade. In this review, the synthesis pathway, internal mechanism and basic physical and chemical properties of melanin-like nanomaterials are systematically classified and evaluated. It also summarizes the application of melanin-like nanoparticles in bioimaging and tumor photothermal therapy (PTT)in detail and discussed the challenges they faced in clinical translation rationally. Overall, melanin-like nanoparticles still have significant room for development in the field of biomedicine and are expected to applied in clinical PTT in the future.

Indexed as

MelaninsPhotothermal TherapyAnimalsDiagnostic ImagingHumansNanomedicineNanoparticlesNeoplasmsMelaninsbiocompatibilitybioimagingclinical applicationmelanin-like nanoparticlesphotothermal conversion abilityphotothermal therapytumor

Identifiers

PMID33401518
PMCPMC7795111

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.