Evidence map›Paper›PMID 33401432›Full record

ArticleToxins2021

Efficient Aflatoxin B1 Sequestration by Yeast Cell Wall Extract and Hydrated Sodium Calcium Aluminosilicate Evaluated Using a Multimodal In-Vitro and Ex-Vivo Methodology.

Alexandros Yiannikouris, Juha Apajalahti, Hannele Kettunen, Suvi Ojanperä, Andrew N W Bell, Jason D Keegan, Colm A Moran

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  12. Toxins · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Alexandros YiannikourisChemistry and Toxicology Division, Center for Animal Nutrigenomic and Applied Animal Nutrition, Alltech Inc., 3031 Nicholasville, KY 40356, USA.ORCID 0000-0001-9220-8201
Juha ApajalahtiAlimetrics Ltd., Koskelontie 19B, 02920 Espoo, Finland.ORCID 0000-0002-6110-129X
Hannele KettunenAlimetrics Ltd., Koskelontie 19B, 02920 Espoo, Finland.
Suvi OjanperäAlimetrics Ltd., Koskelontie 19B, 02920 Espoo, Finland.
Andrew N W BellAlltech Ireland, Sarney, Summerhill Road, A86 X006 Dunboyne, Ireland.ORCID 0000-0002-2607-5938
Jason D KeeganAlltech Ireland, Sarney, Summerhill Road, A86 X006 Dunboyne, Ireland.
Colm A MoranAlltech SARL (France), ZA La Papillionnière, Rue Charles Amand, 14500 Vire, France.ORCID 0000-0001-9135-5074
Alimetrics (Finland) · FIAlltech (Ireland) · IEAlltech (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, adsorption of the carcinogenic mycotoxin aflatoxin B1 (AFB1) by two sequestrants-a yeast cell wall-based adsorbent (YCW) and a hydrated sodium calcium aluminosilicate (HSCAS)-was studied across four laboratory models: (1) an in vitro model from a reference method was employed to quantify the sorption capabilities of both sequestrants under buffer conditions at two pH values using liquid chromatography with fluorescence detection (LC-FLD); (2) in a second in vitro model, the influence of the upper gastrointestinal environment on the mycotoxin sorption capacity of the same two sequestrants was studied using a chronic AFB1 level commonly encountered in the field (10 µg/L and in the presence of feed); (3) the third model used a novel ex vivo approach to measure the absorption of

Indexed as

AdsorptionAflatoxin B1Aluminum SilicatesAnimalsBiological AvailabilityBiological TransportCell ExtractsCell WallIntestinesRatsSaccharomyces cerevisiaeAflatoxin B1Aluminum SilicatesCell Extractssodium calcium aluminosilicate, hydratedabsorptionadsorptionaflatoxin B1bioavailabilityex vivoHSCASin vitromycotoxinsequestrationyeast cell wall extract

Identifiers

PMID33401432
PMCPMC7824576
OpenAlexW3119474138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.