ArticleJournal of the American Geriatrics Society2021
Racial Differences and Temporal Obesity Trends in Heart Failure with Preserved Ejection Fraction.
Article in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- A retrospective study on the clinical significance of cardiac computed tomography in heart failure patients with preserved ejection fraction.Annals of translational medicine · 2022Article
- Temporal Trends and Prognosis of Physical Examination Findings in Patients With Acute Decompensated Heart Failure: The ARIC Study Community Surveillance.Circulation. Heart failure · 2021Article
- Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2021Review
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Authors and funding
11 authors at 6 institutions in 2 countries.
Funding
Abstract
BACKGROUND/
objectivesObesity increases with age, is disproportionately prevalent in black populations, and is associated with heart failure with preserved ejection fraction (HFpEF). An "obesity paradox," or improved survival with obesity, has been reported in patients with HFpEF. The aim of this study was to examine whether racial differences exist in the temporal trends and outcomes associated with obesity among older patients with HFpEF.
designCommunity surveillance of acute decompensated heart failure (ADHF) hospitalizations, sampled by stratified design from 2005 to 2014.
settingAtherosclerosis Risk in Communities Study (NC, MS, MD, MN).
participantsA total of 10,147 weighted hospitalizations for ADHF (64% female, 74% white, mean age 77 years), with ejection fraction ≥50%. MEASUREMENTS: ADHF classified by physician review, HFpEF defined by ejection fraction ≥50%. Body mass index (BMI) calculated from weight at hospital discharge. Obesity defined by BMI ≥30 kg/m
resultsWhen aggregated across 2005-2014, the mean BMI was higher for black compared to white patients (34 vs 30 kg/m
conclusionBlack patients were disproportionately burdened by obesity in this decade-long community surveillance of older hospitalized patients with HFpEF. However, temporal increases in mean BMI and class III obesity prevalence among white patients narrowed the racial difference in recent years. For both races, the worst survival was observed with class III obesity. Effective strategies are needed to manage obesity in patients with HFpEF.
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