Evidence map›Paper›PMID 33400698›Full record

ArticlePLoS neglected tropical diseases2021

Status and forecast of leprosy in the still endemic province of Formosa in northern Argentina.

María R Arnaiz, Mónica S Iglesias, José I Franco, Lucila Arzamendia, María S Santini, Hugo C Recalde

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

María R ArnaizCentro de Diagnóstico e Investigación en Endemo-epidemias, CeNDIE, Ciudad Autónoma de Buenos Aires, Argentina.ORCID 0000-0003-3779-3609
Mónica S IglesiasDepartamento de Biodiversidad y Biología Experimental. Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, FCEyN UBA. Ciudad Universitaria, Ciudad Autónoma de Buenos Aires, Argentina.
José I FrancoPrograma de Control de Leishmaniasis y Lepra de Formosa, PCLyL-F. Dirección de Medicina Preventiva y Prestaciones Especiales, Ministerio de Desarrollo Humano, Formosa, Argentina.
Lucila ArzamendiaPrograma de Control de Leishmaniasis y Lepra de Formosa, PCLyL-F. Dirección de Medicina Preventiva y Prestaciones Especiales, Ministerio de Desarrollo Humano, Formosa, Argentina.
María S SantiniCentro de Diagnóstico e Investigación en Endemo-epidemias, CeNDIE, Ciudad Autónoma de Buenos Aires, Argentina.
Hugo C RecaldePrograma de Control de Leishmaniasis y Lepra de Formosa, PCLyL-F. Dirección de Medicina Preventiva y Prestaciones Especiales, Ministerio de Desarrollo Humano, Formosa, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe province of Formosa, Argentina, is endemic for leprosy. In the present paper, we assessed the trend (T, 2002-2016 time series) and the forecast for 2022 of new case detection rate (NCDR) and determined the spatial distribution of new cases detected (NCD) of leprosy. METHODOLOGY/PRINCIPAL

findingsThis is a descriptive observational study of 713 NCD of leprosy from provincial medical records between January 2002 and December 2016. The whole dataset from the provincial medical record was used to independently estimate the NCDR trends of the general population, age groups, sexes and Departments. This same database was used to estimate the NCDR forecast of the general population for 2022, applying a dynamic linear model with a local linear trend, using the MCMC algorithm. The NCDR was higher in men (p<0.05), increased with age (0.20, 8.17, 21.04, and 29.49 for the 0-14, 15-44, 45-64 and over 65-year-old age groups, respectively; p<0.05) and showed a downward trend (negative values) of estimated slopes for the whole province and each Department. Bermejo Department showed the highest (T:-1.02, 95%CI: [-1.42, -0.66]) and Patiño the lowest decreasing trend (T:-0.45, 95%CI: [-0.74, -0.11]). The NCDR trend for both sexes was similar (T:-0.55, 95%CI: [-0.64, -0.46]), and age groups showed a decreasing trend (S15-44:-103, S45-64:-81, S>65:-61, p<0.05), except for the 0-14 age group (S:-3, p>0.05), which showed no trend. Forecasts predicted that leprosy will not be eliminated by 2022 (3.64, 95%CI: [1.22, 10.25]). CONCLUSIONS/SIGNIFICANCE: Our results highlight the status of leprosy in Formosa and provide information to the provincial public health authorities on high-risk populations, stressing the importance of timely detection of new cases for further elimination of the disease in the province.

Indexed as

AdolescentAdultAgedAlgorithmsArgentinaChildChild, PreschoolForecastingHumansIncidenceInfantInfant, NewbornLeprosyLinear ModelsMaleMiddle Aged

Identifiers

PMID33400698
PMCPMC7785118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.